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ブタ冠状動脈の多核白血球による内皮依存性弛緩作用
http://hdl.handle.net/10191/43053
http://hdl.handle.net/10191/43053d042f785-1c0a-4463-a974-4329eb28dd90
名前 / ファイル | ライセンス | アクション |
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110(5)_177-183.pdf (1.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-08-04 | |||||
タイトル | ||||||
タイトル | ブタ冠状動脈の多核白血球による内皮依存性弛緩作用 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | ブタ冠状動脈の多核白血球による内皮依存性弛緩作用 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polymorphonuclear leukocytes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | coronary artery | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | endothelium | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | endothelium derived hyperpolarizing factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 多核白血球 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 冠状動脈 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 血管内皮 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 内皮由来過分極因子 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Endothelium-Dependent Vasorelaxation of Porcine Coronary Artery by Polymorphonuclear Leukocytes | |||||
著者 |
佐久間, 一弘
× 佐久間, 一弘 |
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著者別名 | ||||||
識別子 | 113667 | |||||
識別子Scheme | WEKO | |||||
姓名 | Sakuma, Kazuhiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The effects of human and porcine polymorphonuclear leukocytes (h-and p-PMLs) on coronary arterial tone were studied using ring segments of the branches of left anterier descending arteries (diam. 1.0~1.3mm, length 2.0mm) isolated from the pig. PMLs (10^6 cells/ml) reduced the tone of the endothelium-intact preparations contracted with 5×10^<-10>-3×10^<-9>M endothelin-1 (ET-1) to a greater extent than that of endothelium-denued ones. The PMLs-induced relaxation of the endothelium-intact preparations were not influenced by various antagonists or inhibitors of nitric oxide production, potassium channel, arachidonate cascade, and adenocine triphosphate dehydroxygenase. However, the relaxation by h-and p-PMLs were almost abolished in preparations treated with Na^+-K^+-ATP-ase inhibitor, 5×10^<-6>M ouabain and contracted with potassium chloride. The findings suggest that neither nitric oxide nor eicosanoids account for the h-and p-PMLs-induced relaxation of porcine coronary artery. It appears that other endothelium derived relaxing factors, such as endothelium derived hyperpolarizing factor, may be involved in the PMLs-induced relaxation. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 110, 号 5, p. 177-183, 発行日 1996-05 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |