{"created":"2021-03-01T06:22:51.081542+00:00","id":18118,"links":{},"metadata":{"_buckets":{"deposit":"50961711-c549-4c4d-8564-f0b3378d8c19"},"_deposit":{"id":"18118","owners":[],"pid":{"revision_id":0,"type":"depid","value":"18118"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00018118","sets":["453:456","471:537:538:1129"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Endothelium-Dependent Vasorelaxation of Porcine Coronary Artery by Polymorphonuclear Leukocytes"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"183","bibliographicPageStart":"177","bibliographicVolumeNumber":"110","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effects of human and porcine polymorphonuclear leukocytes (h-and p-PMLs) on coronary arterial tone were studied using ring segments of the branches of left anterier descending arteries (diam. 1.0～1.3mm, length 2.0mm) isolated from the pig. PMLs (10^6 cells/ml) reduced the tone of the endothelium-intact preparations contracted with 5×10^<-10>-3×10＾<-9>M endothelin-1 (ET-1) to a greater extent than that of endothelium-denued ones. The PMLs-induced relaxation of the endothelium-intact preparations were not influenced by various antagonists or inhibitors of nitric oxide production, potassium channel, arachidonate cascade, and adenocine triphosphate dehydroxygenase. However, the relaxation by h-and p-PMLs were almost abolished in preparations treated with Na＾+-K＾+-ATP-ase inhibitor, 5×10＾<-6>M ouabain and contracted with potassium chloride. The findings suggest that neither nitric oxide nor eicosanoids account for the h-and p-PMLs-induced relaxation of porcine coronary artery. It appears that other endothelium derived relaxing factors, such as endothelium derived hyperpolarizing factor, may be involved in the PMLs-induced relaxation.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"113667","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakuma, Kazuhiro"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐久間, 一弘"}],"nameIdentifiers":[{"nameIdentifier":"113666","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-08"}],"displaytype":"detail","filename":"110(5)_177-183.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110(5)_177-183.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/18118/files/110(5)_177-183.pdf"},"version_id":"9541690d-9ca2-4e3f-b9c0-42a45bb7ca33"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"polymorphonuclear leukocytes","subitem_subject_scheme":"Other"},{"subitem_subject":"coronary artery","subitem_subject_scheme":"Other"},{"subitem_subject":"endothelium","subitem_subject_scheme":"Other"},{"subitem_subject":"endothelium derived hyperpolarizing factor","subitem_subject_scheme":"Other"},{"subitem_subject":"多核白血球","subitem_subject_scheme":"Other"},{"subitem_subject":"冠状動脈","subitem_subject_scheme":"Other"},{"subitem_subject":"血管内皮","subitem_subject_scheme":"Other"},{"subitem_subject":"内皮由来過分極因子","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ブタ冠状動脈の多核白血球による内皮依存性弛緩作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ブタ冠状動脈の多核白血球による内皮依存性弛緩作用"},{"subitem_title":"ブタ冠状動脈の多核白血球による内皮依存性弛緩作用","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1129"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-04"},"publish_date":"2016-08-04","publish_status":"0","recid":"18118","relation_version_is_last":true,"title":["ブタ冠状動脈の多核白血球による内皮依存性弛緩作用"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:49:21.962519+00:00"}