{"_buckets": {"deposit": "36a05df7-24e3-4555-8e7d-f54d45a624f3"}, "_deposit": {"id": "9705", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9705"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00009705", "sets": ["456", "943"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Interleukin-6 Polymorphism and Bronchopulmonary Dysplasia Risk in Very Low Birth Weight Infants"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "255", "bibliographicPageStart": "248", "bibliographicVolumeNumber": "126", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Back ground: This study aimed to evaluate the role of interleukin (IL)-6-634 polymorphism in neonatal disorders such as bronchopulmonary dysplasia (BPD) and periventricular leukomalacia (PVL) in very low birth weight infants. Methods: This prospective cohort study included 202 infants (gestational age at birth was 23-34 weeks and birth weight ranged from 500-1499g). Genotypic analysis (polymerase chain reaction-restriction fragment length polymorphism assays) were performed with DNA extracted from whole-blood samples. Results: Genotype distribution (66.8% CC, 28.2% CG, and 5.0% GG) in this study was similar to that in the adult Japanese population. The duration of O_2 therapy in infants with CG/GG genotypes was significantly longer than that in infants with the CC genotype (CG/GG vs. CC: 40.3±52.2 days vs. 28.4±32.6 days, p \u003c0.05). Infants with CG/GG genotypes were more likely to have received postnatal corticosteroid therapy for BPD than those with the CC genotype (CG/GG vs. CC: 20.9% vs. ll.1%, p =0.05). There was no significant difference in the frequency of PVL among IL-6-634 polymorphisms. Conclusions: This study showed an association between IL-6-634 polymorphism and the duration of oxygen therapy for BPD in very low birth weight infants. This finding suggests that the IL-6-634 polymorphism G allele is an aggravating factor of BPD. IL-6-634 polymorphism is not associated with PVL.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "67090", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Usuda, Touhei"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "臼田, 東平"}], "nameIdentifiers": [{"nameIdentifier": "67089", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "126(5)_248-255.pdf", "filesize": [{"value": "1.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1100000.0, "url": {"label": "126(5)_248-255.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/9705/files/126(5)_248-255.pdf"}, "version_id": "baecfdee-6fa1-4441-80ac-0f214f76ff64"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "bronchopulmonary dysplasia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "periventricular leukomalacia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gene polymorphism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "interleukin-6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "very low birth weight infant", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "極低出生体重児における慢性肺疾患とインターロイキン6遺伝子多型との関連性", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "極低出生体重児における慢性肺疾患とインターロイキン6遺伝子多型との関連性"}, {"subitem_title": "極低出生体重児における慢性肺疾患とインターロイキン6遺伝子多型との関連性", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "943"], "permalink_uri": "http://hdl.handle.net/10191/31501", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-01-09"}, "publish_date": "2015-01-09", "publish_status": "0", "recid": "9705", "relation": {}, "relation_version_is_last": true, "title": ["極低出生体重児における慢性肺疾患とインターロイキン6遺伝子多型との関連性"], "weko_shared_id": null}