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5 皮膚科領域 乾癬における生物学的製剤治療 (シンポジウム 各科領域における生物学的製剤の現況と展望, 第720回新潟医学会)
http://hdl.handle.net/10191/49655
2b7b9335-70ac-46c2-a686-9fd7fc6c8935
名前 / ファイル | ライセンス | アクション | |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2018-02-28 | |||||
タイトル | ||||||
タイトル | 5 皮膚科領域 乾癬における生物学的製剤治療 (シンポジウム 各科領域における生物学的製剤の現況と展望, 第720回新潟医学会) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 5 皮膚科領域 乾癬における生物学的製剤治療 (シンポジウム 各科領域における生物学的製剤の現況と展望, 第720回新潟医学会) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 乾癬 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 生物学的製剤 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Biologic Therapy for Psoriasis | |||||
著者 |
藤本, 篤
× 藤本, 篤× 阿部, 理一郎 |
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著者別名 | ||||||
識別子 | ||||||
識別子 | 57744 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | Fujimoto, Atsushi | |||||
著者別名 | ||||||
識別子 | ||||||
識別子 | 57745 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | Abe, Riichiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 生物学的製剤の登場は,既存の治療で難渋していた重症乾癬患者における皮疹のコントロールや乾癬性関節炎患者における関節破壊の進展抑制を可能にした.現在わが国で乾癬に対して使用可能な生物学的製剤は6剤あり,標的とする分子,抗体の種類,作用機序,投与経路や投与間隔など,それぞれに特徴がある.いずれの製剤も有効性は高いが,反面,副作用や高額な費用などの問題があり,適応症例を慎重に選択した上で,十分な説明と同意に基づいて投与を決定する必要がある.現在当科では,既存治療に抵抗性の症例,重症例や強い関節症状を有する症例を対象に,インフリキシマブ,アダリムマブ,ウステキヌマブ,セクキヌマブ,イキセキズマブの5剤を病型,年齢,合併症,利便性などを考慮して選択している.これまで大きな有害事象はなく,多くの症例において期待した効果を得られている.今後もさらに新規の生物学的製剤の開発が進行中であり,各製剤の特徴を生かした有効な使用方法の確立のためのデータの蓄積と解析が待たれる. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 131, 号 8, p. 464-469, 発行日 2017-08 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |