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Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri
http://hdl.handle.net/10191/33554
http://hdl.handle.net/10191/33554edf26165-4709-4f0b-95b2-d3888f5c6220
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-10-06 | |||||
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タイトル | Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri | |||||
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言語 | en | |||||
タイトル | Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri | |||||
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言語 | eng | |||||
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資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Ikarashi, Toshihiko
× Ikarashi, Toshihiko |
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内容記述タイプ | Abstract | |||||
内容記述 | The histochemical analyses of glycoproteins were performed on specimens of endocervical type adenocarcinoma of uterine cervical carcinoma (EA) (40 cases) and normal cervices (19 cases) by the following methods: (1) Modified Schiff stains for sialates, including both Periodic Acid-Thionin Schiff/Potassium hydroxide/Periodic Acid-Schiff stain (PAT/KOH/PAS) and Mild Oxydation-Thionin Schiff/Periodic acid Borohydride/Potassium hydroxide/Periodic Acid-Schiff stain (MOT/PBT/KOH/PAS), (2) Immuno-histochemical stains with biotinylated lectins, including Dolichos Biflorus Aggulutinin (DBA), Griffonia Simplicifolia I (GS-I), Ulex Europaeus Agglutinin (UEA-I), Peanut Aggulutinin (PNA), Concanavalin A (Con A), Ricinus Communis Agglutinin I (RCA 120), Soybean Aggulutinin (SBA), and wheat germ aggulutinin (WGA). In the modified Schiff stains, tumor cells contained o-acetylated sialates or frequently lost the ability to produce sialates, while the normal endocervical cells produced predominantly non-acetylated sialates. Abrupt transition was also confirmed by these stainings. Based on the lectin study, the frequency of the positive reaction to PNA and Con A was statistically high in EA (p<0.005). The nuclear stratification index (NSI) was calculated positive in the cancerous glands for histochemical reactions, and the NSI of EA's was higher than that of normal cervices (P <0.05). These histochemical reactions were statistically significance and indicated both abrupt transition and NSI as important atypisms for cancer diagnosis. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 36, 号 2, p. 75-84, 発行日 1988-10 |
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出版者 | Niigata University School of Medicine | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |