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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.36 No.2

Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri

http://hdl.handle.net/10191/33554
http://hdl.handle.net/10191/33554
edf26165-4709-4f0b-95b2-d3888f5c6220
名前 / ファイル ライセンス アクション
36(2)_75-84.pdf 36(2)_75-84.pdf (2.0 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-10-06
タイトル
タイトル Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri
タイトル
タイトル Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri
言語 en
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Ikarashi, Toshihiko

× Ikarashi, Toshihiko

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Ikarashi, Toshihiko

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内容記述タイプ Abstract
内容記述 The histochemical analyses of glycoproteins were performed on specimens of endocervical type adenocarcinoma of uterine cervical carcinoma (EA) (40 cases) and normal cervices (19 cases) by the following methods: (1) Modified Schiff stains for sialates, including both Periodic Acid-Thionin Schiff/Potassium hydroxide/Periodic Acid-Schiff stain (PAT/KOH/PAS) and Mild Oxydation-Thionin Schiff/Periodic acid Borohydride/Potassium hydroxide/Periodic Acid-Schiff stain (MOT/PBT/KOH/PAS), (2) Immuno-histochemical stains with biotinylated lectins, including Dolichos Biflorus Aggulutinin (DBA), Griffonia Simplicifolia I (GS-I), Ulex Europaeus Agglutinin (UEA-I), Peanut Aggulutinin (PNA), Concanavalin A (Con A), Ricinus Communis Agglutinin I (RCA 120), Soybean Aggulutinin (SBA), and wheat germ aggulutinin (WGA). In the modified Schiff stains, tumor cells contained o-acetylated sialates or frequently lost the ability to produce sialates, while the normal endocervical cells produced predominantly non-acetylated sialates. Abrupt transition was also confirmed by these stainings. Based on the lectin study, the frequency of the positive reaction to PNA and Con A was statistically high in EA (p<0.005). The nuclear stratification index (NSI) was calculated positive in the cancerous glands for histochemical reactions, and the NSI of EA's was higher than that of normal cervices (P <0.05). These histochemical reactions were statistically significance and indicated both abrupt transition and NSI as important atypisms for cancer diagnosis.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 36, 号 2, p. 75-84, 発行日 1988-10
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
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