{"created":"2021-03-01T06:10:34.885850+00:00","id":6663,"links":{},"metadata":{"_buckets":{"deposit":"7b61fee8-6c27-482c-88c2-9e5671790815"},"_deposit":{"id":"6663","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6663"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006663","sets":["453:456","471:537:568:652"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"84","bibliographicPageStart":"75","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The histochemical analyses of glycoproteins were performed on specimens of endocervical type adenocarcinoma of uterine cervical carcinoma (EA) (40 cases) and normal cervices (19 cases) by the following methods: (1) Modified Schiff stains for sialates, including both Periodic Acid-Thionin Schiff/Potassium hydroxide/Periodic Acid-Schiff stain (PAT/KOH/PAS) and Mild Oxydation-Thionin Schiff/Periodic acid Borohydride/Potassium hydroxide/Periodic Acid-Schiff stain (MOT/PBT/KOH/PAS), (2) Immuno-histochemical stains with biotinylated lectins, including Dolichos Biflorus Aggulutinin (DBA), Griffonia Simplicifolia I (GS-I), Ulex Europaeus Agglutinin (UEA-I), Peanut Aggulutinin (PNA), Concanavalin A (Con A), Ricinus Communis Agglutinin I (RCA 120), Soybean Aggulutinin (SBA), and wheat germ aggulutinin (WGA). In the modified Schiff stains, tumor cells contained o-acetylated sialates or frequently lost the ability to produce sialates, while the normal endocervical cells produced predominantly non-acetylated sialates. Abrupt transition was also confirmed by these stainings. Based on the lectin study, the frequency of the positive reaction to PNA and Con A was statistically high in EA (p<0.005). The nuclear stratification index (NSI) was calculated positive in the cancerous glands for histochemical reactions, and the NSI of EA's was higher than that of normal cervices (P <0.05). These histochemical reactions were statistically significance and indicated both abrupt transition and NSI as important atypisms for cancer diagnosis.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ikarashi, Toshihiko"}],"nameIdentifiers":[{"nameIdentifier":"53861","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"36(2)_75-84.pdf","filesize":[{"value":"2.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"36(2)_75-84.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6663/files/36(2)_75-84.pdf"},"version_id":"e0802e8e-e260-4f6e-b6d0-873756244f1b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri"},{"subitem_title":"Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","652"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-10-06"},"publish_date":"2015-10-06","publish_status":"0","recid":"6663","relation_version_is_last":true,"title":["Histochemical and morphometric studies of endocervical type adenocarcinoma in the cervix uteri"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:57.871073+00:00"}