{"_buckets": {"deposit": "38a8804a-e6ba-4182-a398-76aeee1a4499"}, "_deposit": {"id": "6636", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6636"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006636"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "39", "bibliographicPageStart": "37", "bibliographicVolumeNumber": "38", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Histochemical and immunohistochemical analyses were carried out to determine the relationships of iron accumulation in hepatocellular carcinoma and hepatitis B virus antigens using 300 autopsy cases obtained from Nagasaki University Hospital. Iron accumulation in hepatocellular carcinoma was studied with Prussian blue reaction, and a positive reaction for hepatitis B core antigen and hepatitis B surface antigen were investigated by immunoperoxidase methods. Two cases of iron positive were observed in the cancerous tissue. These cases were hepatitis B core antigen-positive in the cancerous tissue, but hepatitis B surface antigen was negative in the same area. Therefore, hepatocellular carcinoma with hepatitis B surface antigen does not show iron accumulation, whereas the same tumor with hepatitis B core antigen is accompanied by iron accumulation. These findings suggest that hepatitis B core antigen produces the degeneration or collapse of the genes of hepatocellular carcinoma resulting in an iron metabolism disorder.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Senba, Masachika"}], "nameIdentifiers": [{"nameIdentifier": "53767", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawai, Kioko"}], "nameIdentifiers": [{"nameIdentifier": "53768", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "38(1)_37-39.pdf", "filesize": [{"value": "697.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 697700.0, "url": {"label": "38(1)_37-39.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6636/files/38(1)_37-39.pdf"}, "version_id": "2375bdb4-b42e-4b46-ab52-0586381ccd36"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen"}, {"subitem_title": "Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/647"], "permalink_uri": "http://hdl.handle.net/10191/33475", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-10-01"}, "publish_date": "2015-10-01", "publish_status": "0", "recid": "6636", "relation": {}, "relation_version_is_last": true, "title": ["Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen"], "weko_shared_id": null}