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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.38 No.1

Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen

http://hdl.handle.net/10191/33475
http://hdl.handle.net/10191/33475
62781100-e8a1-4db2-8389-d6cfd43da67d
名前 / ファイル ライセンス アクション
38(1)_37-39.pdf 38(1)_37-39.pdf (697.7 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-10-01
タイトル
タイトル Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen
タイトル
言語 en
タイトル Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Senba, Masachika

× Senba, Masachika

WEKO 53767

Senba, Masachika

Search repository
Kawai, Kioko

× Kawai, Kioko

WEKO 53768

Kawai, Kioko

Search repository
抄録
内容記述タイプ Abstract
内容記述 Histochemical and immunohistochemical analyses were carried out to determine the relationships of iron accumulation in hepatocellular carcinoma and hepatitis B virus antigens using 300 autopsy cases obtained from Nagasaki University Hospital. Iron accumulation in hepatocellular carcinoma was studied with Prussian blue reaction, and a positive reaction for hepatitis B core antigen and hepatitis B surface antigen were investigated by immunoperoxidase methods. Two cases of iron positive were observed in the cancerous tissue. These cases were hepatitis B core antigen-positive in the cancerous tissue, but hepatitis B surface antigen was negative in the same area. Therefore, hepatocellular carcinoma with hepatitis B surface antigen does not show iron accumulation, whereas the same tumor with hepatitis B core antigen is accompanied by iron accumulation. These findings suggest that hepatitis B core antigen produces the degeneration or collapse of the genes of hepatocellular carcinoma resulting in an iron metabolism disorder.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 38, 号 1, p. 37-39, 発行日 1990-03
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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