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Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen
http://hdl.handle.net/10191/33475
http://hdl.handle.net/10191/3347562781100-e8a1-4db2-8389-d6cfd43da67d
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-10-01 | |||||
タイトル | ||||||
タイトル | Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Iron Accumulation in Hepatocellular Carcinoma and the Role of Hepatitis B Core Antigen | |||||
言語 | ||||||
言語 | eng | |||||
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資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Senba, Masachika
× Senba, Masachika× Kawai, Kioko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Histochemical and immunohistochemical analyses were carried out to determine the relationships of iron accumulation in hepatocellular carcinoma and hepatitis B virus antigens using 300 autopsy cases obtained from Nagasaki University Hospital. Iron accumulation in hepatocellular carcinoma was studied with Prussian blue reaction, and a positive reaction for hepatitis B core antigen and hepatitis B surface antigen were investigated by immunoperoxidase methods. Two cases of iron positive were observed in the cancerous tissue. These cases were hepatitis B core antigen-positive in the cancerous tissue, but hepatitis B surface antigen was negative in the same area. Therefore, hepatocellular carcinoma with hepatitis B surface antigen does not show iron accumulation, whereas the same tumor with hepatitis B core antigen is accompanied by iron accumulation. These findings suggest that hepatitis B core antigen produces the degeneration or collapse of the genes of hepatocellular carcinoma resulting in an iron metabolism disorder. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 38, 号 1, p. 37-39, 発行日 1990-03 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |