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Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood
http://hdl.handle.net/10191/33482
http://hdl.handle.net/10191/33482b7412014-85f8-4686-a334-ddbe64bf6262
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
38(2)_91-95.pdf (787.9 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-10-01 | |||||
| タイトル | ||||||
| タイトル | Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood | |||||
| タイトル | ||||||
| タイトル | Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Asami, Tadashi
× Asami, Tadashi× Nishihara, Touru× Sakai, Kaoru |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To clarify the changes in plasma proteinase inhibitors in renal diseases, we measured the activity of plasma α_1-antichymotrypsin(α_1-Achy) under sueh conditions. The level of plasma α_1-Achy activity was found to be significantly lower in idiopathic nephrotic syndrome (INS) at relapse than in INS during remission, as well as in patients with chance proteinuria and/or hematuria (CPH) and in normal control subjects. The α_1-Achy activity in CPH was signiificantly elevated compared with that in INS (p<0.001) and normal controls (p<0.001). A significant inverse correlation was noted between the plasma α_1-Achy activity and the inhibitory effect of plasma on lymphocyte blastogenesis induced by Concanavalin A. Although the mechanism is unclear, the elevation of α_1-Achy in CPH (implicated in various types of glomerulonephritis) may be one of the responses of the body to counteract inflammatory processes by inactivating proteinase(s) released from infiltrating and/or proliferating cells in the glomeruli. The decreased plasma α_1-Achy level in INS may contribute to the depressed cellular immunity seen in INS. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 38, 号 2, p. 91-95, 発行日 1990-06 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Asami, Tadashi, Nishihara, Touru, Sakai, Kaoru, 1990, Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood: Niigata University School of Medicine, 91–95 p.
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