{"_buckets": {"deposit": "892bf9e2-d948-40b9-b609-0a6fa4cb6a66"}, "_deposit": {"id": "6630", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6630"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006630", "sets": ["456", "646"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "95", "bibliographicPageStart": "91", "bibliographicVolumeNumber": "38", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "To clarify the changes in plasma proteinase inhibitors in renal diseases, we measured the activity of plasma α_1-antichymotrypsin(α_1-Achy) under sueh conditions. The level of plasma α_1-Achy activity was found to be significantly lower in idiopathic nephrotic syndrome (INS) at relapse than in INS during remission, as well as in patients with chance proteinuria and/or hematuria (CPH) and in normal control subjects. The α_1-Achy activity in CPH was signiificantly elevated compared with that in INS (p\u003c0.001) and normal controls (p\u003c0.001). A significant inverse correlation was noted between the plasma α_1-Achy activity and the inhibitory effect of plasma on lymphocyte blastogenesis induced by Concanavalin A. Although the mechanism is unclear, the elevation of α_1-Achy in CPH (implicated in various types of glomerulonephritis) may be one of the responses of the body to counteract inflammatory processes by inactivating proteinase(s) released from infiltrating and/or proliferating cells in the glomeruli. The decreased plasma α_1-Achy level in INS may contribute to the depressed cellular immunity seen in INS.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Asami, Tadashi"}], "nameIdentifiers": [{"nameIdentifier": "53745", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishihara, Touru"}], "nameIdentifiers": [{"nameIdentifier": "53746", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Kaoru"}], "nameIdentifiers": [{"nameIdentifier": "53747", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "38(2)_91-95.pdf", "filesize": [{"value": "787.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 787900.0, "url": {"label": "38(2)_91-95.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6630/files/38(2)_91-95.pdf"}, "version_id": "660bb2dc-0d18-4166-b69a-9bb233eac9d8"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood"}, {"subitem_title": "Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "646"], "permalink_uri": "http://hdl.handle.net/10191/33482", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-10-01"}, "publish_date": "2015-10-01", "publish_status": "0", "recid": "6630", "relation": {}, "relation_version_is_last": true, "title": ["Plasma α_1-antichymotrypsin Activity in Renal Diseases of Childhood"], "weko_shared_id": null}