{"_buckets": {"deposit": "8a1c94f6-5c92-499b-bf2c-894be29cdaeb"}, "_deposit": {"id": "6518", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6518"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006518"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "200", "bibliographicPageStart": "197", "bibliographicVolumeNumber": "41", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "In order to diagnose hepatocellular carcinoma (HCC), plasma levels of protein induced by vitamin K absence or antagonist-II (PIVKA-II) were determined by an enzyme-linked immunosorbent assay (ELISA). Positive reaction was noted in 34 (68%) of 50 patients with HCC, with PIVKA-II serving as an useful tumor marker in the estimation of HCC staging. On the other hand, the administration of vitamin K and the presence of jaundice were found to be important factors that affect plasma PIVKA-II levels. The administration of antibiotics with N-methylthiotetrazole at a dosage of 2 g/day for 3 days (total 6 g) did not seem to increase plasma concentrations of PIVKA-II levels. Thus, the measurement of the plasma PIVKA-II levels was useful for the diagnosis of HCC except for the disturbance of vitamin K utilization.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Soga, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "53304", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Arai, Futoshi"}], "nameIdentifiers": [{"nameIdentifier": "53305", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsuruya, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "53306", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Aikawa, Keiko"}], "nameIdentifiers": [{"nameIdentifier": "53307", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toshima, Muneatsu"}], "nameIdentifiers": [{"nameIdentifier": "53308", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shibasaki, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "53309", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Aoyagi, Yutaka"}], "nameIdentifiers": [{"nameIdentifier": "53310", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "41(4)_197-200.pdf", "filesize": [{"value": "558.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 558400.0, "url": {"label": "41(4)_197-200.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6518/files/41(4)_197-200.pdf"}, "version_id": "e52b4e49-f047-4513-bf5e-fdccfc1946d3"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma"}, {"subitem_title": "Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/629"], "permalink_uri": "http://hdl.handle.net/10191/33334", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-09-11"}, "publish_date": "2015-09-11", "publish_status": "0", "recid": "6518", "relation": {}, "relation_version_is_last": true, "title": ["Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma"], "weko_shared_id": null}