{"created":"2021-03-01T06:10:25.723332+00:00","id":6518,"links":{},"metadata":{"_buckets":{"deposit":"8a1c94f6-5c92-499b-bf2c-894be29cdaeb"},"_deposit":{"id":"6518","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6518"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006518","sets":["453:456","471:537:568:629"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"200","bibliographicPageStart":"197","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In order to diagnose hepatocellular carcinoma (HCC), plasma levels of protein induced by vitamin K absence or antagonist-II (PIVKA-II) were determined by an enzyme-linked immunosorbent assay (ELISA). Positive reaction was noted in 34 (68%) of 50 patients with HCC, with PIVKA-II serving as an useful tumor marker in the estimation of HCC staging. On the other hand, the administration of vitamin K and the presence of jaundice were found to be important factors that affect plasma PIVKA-II levels. The administration of antibiotics with N-methylthiotetrazole at a dosage of 2 g/day for 3 days (total 6 g) did not seem to increase plasma concentrations of PIVKA-II levels. Thus, the measurement of the plasma PIVKA-II levels was useful for the diagnosis of HCC except for the disturbance of vitamin K utilization.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Soga, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"53304","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Arai, Futoshi"}],"nameIdentifiers":[{"nameIdentifier":"53305","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuruya, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"53306","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aikawa, Keiko"}],"nameIdentifiers":[{"nameIdentifier":"53307","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Toshima, Muneatsu"}],"nameIdentifiers":[{"nameIdentifier":"53308","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shibasaki, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"53309","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoyagi, Yutaka"}],"nameIdentifiers":[{"nameIdentifier":"53310","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"41(4)_197-200.pdf","filesize":[{"value":"558.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"41(4)_197-200.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6518/files/41(4)_197-200.pdf"},"version_id":"e52b4e49-f047-4513-bf5e-fdccfc1946d3"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma"},{"subitem_title":"Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","629"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-09-11"},"publish_date":"2015-09-11","publish_status":"0","recid":"6518","relation_version_is_last":true,"title":["Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:51.738280+00:00"}