{"_buckets": {"deposit": "2bb94b7f-7ea3-4524-ac79-88fa190bc6ab"}, "_deposit": {"id": "6456", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6456"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006456"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1995-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "216", "bibliographicPageStart": "211", "bibliographicVolumeNumber": "43", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Problem: What are the possible underlying mechanisms of immunotherapy for unexplained recurrent abortion using spouse\u0027s cells? Methods: The reactivity of lymphocytes against spouse\u0027s lymphocytes in a mixed lymphocyte culture reaction (MLR) was serially evaluated in married female patients with unexplained recurrent abortion who underwent immunotherapy. Results: Reactivity against the spouse\u0027s lymphocytes significantly decreased after immunotherapy compared with that before therapy (n=19, p\u003c0.01, Wilcoxon test). Reactivity during the first trimester of the new pregnancy was also significantly lower than that before immunotherapy in married female patients with a successful outcome (n=9, p\u003c 0.05, Wilcoxon test). Reactivity in MLR, however, was significantly higher in married female patients who subsequently had repeated spontaneous abortion (n=4, p\u003c0.05, Wilcoxon test). Conclusion: It is suggested that the attenuation of the reactivity against the spouse\u0027s lymphocytes might be implicated in the successful pregnancy of patients with unexplained recurrent abortion who underwent the immunotherapy.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kazama, Yoshiki"}], "nameIdentifiers": [{"nameIdentifier": "53026", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takakuwa, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "53027", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Kenichi"}], "nameIdentifiers": [{"nameIdentifier": "53028", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "43(4)_211-216.pdf", "filesize": [{"value": "572.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 572500.0, "url": {"label": "43(4)_211-216.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6456/files/43(4)_211-216.pdf"}, "version_id": "d63bfa10-856c-437c-ae6d-69ef8111fb70"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "recurrent abortion", "subitem_subject_scheme": "Other"}, {"subitem_subject": "immunotherapy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MLR", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "MLR Reactivity against Spouse\u0027s Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse\u0027s Cells", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "MLR Reactivity against Spouse\u0027s Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse\u0027s Cells"}, {"subitem_title": "MLR Reactivity against Spouse\u0027s Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse\u0027s Cells", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/621"], "permalink_uri": "http://hdl.handle.net/10191/33219", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-08-31"}, "publish_date": "2015-08-31", "publish_status": "0", "recid": "6456", "relation": {}, "relation_version_is_last": true, "title": ["MLR Reactivity against Spouse\u0027s Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse\u0027s Cells"], "weko_shared_id": null}