{"created":"2021-03-01T06:10:21.816907+00:00","id":6456,"links":{},"metadata":{"_buckets":{"deposit":"2bb94b7f-7ea3-4524-ac79-88fa190bc6ab"},"_deposit":{"id":"6456","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6456"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006456","sets":["453:456","471:537:568:621"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"216","bibliographicPageStart":"211","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Problem: What are the possible underlying mechanisms of immunotherapy for unexplained recurrent abortion using spouse's cells? Methods: The reactivity of lymphocytes against spouse's lymphocytes in a mixed lymphocyte culture reaction (MLR) was serially evaluated in married female patients with unexplained recurrent abortion who underwent immunotherapy. Results: Reactivity against the spouse's lymphocytes significantly decreased after immunotherapy compared with that before therapy (n=19, p<0.01, Wilcoxon test). Reactivity during the first trimester of the new pregnancy was also significantly lower than that before immunotherapy in married female patients with a successful outcome (n=9, p< 0.05, Wilcoxon test). Reactivity in MLR, however, was significantly higher in married female patients who subsequently had repeated spontaneous abortion (n=4, p<0.05, Wilcoxon test). Conclusion: It is suggested that the attenuation of the reactivity against the spouse's lymphocytes might be implicated in the successful pregnancy of patients with unexplained recurrent abortion who underwent the immunotherapy.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kazama, Yoshiki"}],"nameIdentifiers":[{"nameIdentifier":"53026","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takakuwa, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"53027","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Kenichi"}],"nameIdentifiers":[{"nameIdentifier":"53028","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"43(4)_211-216.pdf","filesize":[{"value":"572.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"43(4)_211-216.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6456/files/43(4)_211-216.pdf"},"version_id":"d63bfa10-856c-437c-ae6d-69ef8111fb70"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"recurrent abortion","subitem_subject_scheme":"Other"},{"subitem_subject":"immunotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"MLR","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells"},{"subitem_title":"MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","621"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-08-31"},"publish_date":"2015-08-31","publish_status":"0","recid":"6456","relation_version_is_last":true,"title":["MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:44.381771+00:00"}