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Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations?
http://hdl.handle.net/10191/33180
http://hdl.handle.net/10191/3318099484c70-eafb-40d8-8233-50abeaf34042
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
44(4)_187-191.pdf (666.5 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-08-27 | |||||
| タイトル | ||||||
| タイトル | Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations? | |||||
| タイトル | ||||||
| タイトル | Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations? | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cytokines | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | IL-6 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | TNF-a | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | operation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | tissue injury | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Sato, Nobuaki
× Sato, Nobuaki× Ohkawa, Akira× Oyamatsu, Manabu× Koyama, Yu× Kayama, Seiji× Hatakeyama, Katsuyoshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Serum IL-6 concentration is a sensitive, early marker of tissue damage. However, the importance of locally acting cytokines often outweighs that of systemic cytokines measured in the serum. Study design: We investigated the relationship between the type of surgical procedure and the response of regional TNF-a and IL-6 concentrations. We measured changes in cytokine concentrations in the wound fluid of 14 patients following transthoracic esophagectomy for carcinoma of the esophagus and compared them with those of 6 patients who underwent breast surgery. Results: A significant difference in the time course of changes in the TNF-a concentrations was found between the esophagectomy and breast surgery groups. Regional IL-6 concentrations were significantly higher in the esophagectomy group than in the breast surgery group during the first 72 h postoperatively. Conclusion: Our results suggest that the magnitude of tissue injury influences regional TNF-a and IL-6 concentrations as well as systemic serum IL-6 concentrations, and that the measurement of regional cytokines may lead to a better understanding of the cytokine response mechanism. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 44, 号 4, p. 187-191, 発行日 1996-12 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
