{"_buckets": {"deposit": "ddb6c5c6-5d68-44f8-a202-d8d5e6184784"}, "_deposit": {"id": "6418", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6418"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006418"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1996-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "191", "bibliographicPageStart": "187", "bibliographicVolumeNumber": "44", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Background: Serum IL-6 concentration is a sensitive, early marker of tissue damage. However, the importance of locally acting cytokines often outweighs that of systemic cytokines measured in the serum. Study design: We investigated the relationship between the type of surgical procedure and the response of regional TNF-a and IL-6 concentrations. We measured changes in cytokine concentrations in the wound fluid of 14 patients following transthoracic esophagectomy for carcinoma of the esophagus and compared them with those of 6 patients who underwent breast surgery. Results: A significant difference in the time course of changes in the TNF-a concentrations was found between the esophagectomy and breast surgery groups. Regional IL-6 concentrations were significantly higher in the esophagectomy group than in the breast surgery group during the first 72 h postoperatively. Conclusion: Our results suggest that the magnitude of tissue injury influences regional TNF-a and IL-6 concentrations as well as systemic serum IL-6 concentrations, and that the measurement of regional cytokines may lead to a better understanding of the cytokine response mechanism.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sato, Nobuaki"}], "nameIdentifiers": [{"nameIdentifier": "52818", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohkawa, Akira"}], "nameIdentifiers": [{"nameIdentifier": "52819", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oyamatsu, Manabu"}], "nameIdentifiers": [{"nameIdentifier": "52820", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koyama, Yu"}], "nameIdentifiers": [{"nameIdentifier": "52821", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kayama, Seiji"}], "nameIdentifiers": [{"nameIdentifier": "52822", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hatakeyama, Katsuyoshi"}], "nameIdentifiers": [{"nameIdentifier": "52823", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "44(4)_187-191.pdf", "filesize": [{"value": "666.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 666500.0, "url": {"label": "44(4)_187-191.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6418/files/44(4)_187-191.pdf"}, "version_id": "bc498588-e084-41ce-9092-47fbc1532970"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "cytokines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TNF-a", "subitem_subject_scheme": "Other"}, {"subitem_subject": "operation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "tissue injury", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations?", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations?"}, {"subitem_title": "Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations?", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/617"], "permalink_uri": "http://hdl.handle.net/10191/33180", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-08-27"}, "publish_date": "2015-08-27", "publish_status": "0", "recid": "6418", "relation": {}, "relation_version_is_last": true, "title": ["Does the Magnitude of the Operative Injury Influence Postoperative Regional TNF-a and IL-6 Concentrations?"], "weko_shared_id": null}