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A Glucose Receptive Field of Hepatic Vagal Afferent that Inhibits Gastric Acid Secretion in Rats
http://hdl.handle.net/10191/1922
http://hdl.handle.net/10191/19224c674f0c-64bb-44e0-b1f3-476bd5739bee
名前 / ファイル | ライセンス | アクション |
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KJ00000007322.pdf (3.0 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-05-10 | |||||
タイトル | ||||||
タイトル | A Glucose Receptive Field of Hepatic Vagal Afferent that Inhibits Gastric Acid Secretion in Rats | |||||
タイトル | ||||||
タイトル | A Glucose Receptive Field of Hepatic Vagal Afferent that Inhibits Gastric Acid Secretion in Rats | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | portal vein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | glucose | |||||
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主題Scheme | Other | |||||
主題 | vagal nerve | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | acid output | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rat | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
SAKAGUCHI, Takeo
× SAKAGUCHI, Takeo× LIU, Lili× OHTAKE, Masahiro× HATAKEYAMA, Katsuyoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Changes in gastric acid output induced by intra- and extrahepatic portal injections of glucose were examined in the liver using intact and hepatectomized (40 and 66%) rats under general anesthesia. Acid output was decreased in a dose-dependent fashion 3 min after a glucose injection into the intra- and extrahepatic portal vein in the intact liver. The acid decrease was blocked by hepatic branch vagotomy. The aci dresponse induced by the extrahepatic portal injection of glucose was not influenced by lidocaine anesthesia of the extrahepatic portal walls, but was diminished by a 40% hepatectomy, and completely blocked by a 66% hepatectomy. Hepatic branch splanchnicotomy failed to modify the acid response. Plasma glucose levels before and after the portal glucose injection and liver functional parameters in the blood under hepatectomy during the experiments were unchanged. Since it is known that there are no vagal receptors in the hepatic parenchyma, these results suggested that the receptive field of the hepatic vagal afferents which inhibits gastric acid secretion mainly originates in the intrahepatic portal structures. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 50, 号 2, p. 97-101, 発行日 2002-06 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |