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正常妊娠におけるGanglioside GM2の組織局在, 血中動態および対応抗体の解析
http://hdl.handle.net/10191/41256
http://hdl.handle.net/10191/41256e3b72773-ed76-4024-93e3-d322d667b6a4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
103(5)_380-391.pdf (4.4 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-04-11 | |||||
| タイトル | ||||||
| タイトル | 正常妊娠におけるGanglioside GM2の組織局在, 血中動態および対応抗体の解析 | |||||
| タイトル | ||||||
| タイトル | 正常妊娠におけるGanglioside GM2の組織局在, 血中動態および対応抗体の解析 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ganglioside | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | GM2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Placenta | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Decidua | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Pregnancy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ガングリオシド | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 胎盤 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 脱落膜 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 妊娠 | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Analysis of GM2 and Anti-GM2 Antibody as to the Kinetics in Pregnant Sera and the Tissue Localization in Placenta and Decidua | |||||
| 著者 |
鈴木, 孝明
× 鈴木, 孝明 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 138487 | |||||
| 姓名 | Suzuki, Takaaki | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Oncofetal antigen (OFA-I), an antigen common to the fetal brain and some malignant tumors (derived from ectoderm), is immunogenic in human and anti-OFA-I antibody appears in sera of not only malignant patients but also pregnant women. Biochemical analysis revealed that OFA-I is gangliosides GM2 and GD2. In the present study, GM2 and anti-GM2 antibody were investigated as to the kinetics in pregnant sera and the tissue localization in placenta and decidua. The results obtained were as follows; (1) GM2 was detected by thin layer chromatogram-immunostaining methods in the gangliosides extracted from decidua and from term placenta. GM2 was, however, undetectable in the gangliosides extracted from villi at early stage. (2) A concentration of GM2 was 64.9 pmol/ml (mean) in pregnant sera and 10.9 pmol/ml (mean) in cord sera. GM2 was not measurable in sera of non-pregnant women. (3) In immunohistological analysis for GM2, positive findings were observed in decidua and in villous stroma of term placenta. In contrast, no distinct positive findings were observed in trophoblast at any stage. (4) Anti-GM2 antibody appeared in pregnant sera of early stage and was detectable up to 5th day of postpartum. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 103, 号 5, p. 380-391, 発行日 1989-05 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
鈴木, 孝明, 1989, 正常妊娠におけるGanglioside GM2の組織局在, 血中動態および対応抗体の解析: 新潟医学会, 380–391 p.
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