{"_buckets": {"deposit": "6cddec24-60ba-47ea-96d7-dd15faf9e36e"}, "_deposit": {"id": "22910", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22910"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022910"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Establishment of mouse and human IL-3 producing T cell lines and a specific technique for quantification of IL-3 activity by mast cell-colony formation in soft agar.(Recent Advances in Research on the Cell Growth Factors)"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "363", "bibliographicPageStart": "354", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and increase in hemopoietic stem cells and progenitors in the spleen. Serum and spleen-conditioned medium of the mouse induced CFU-mix, BFU-E and GM-CFC derived colonies, and supported growth of IL-3 dependent cell lines, FDC-P2 and DA-1. They also induced mast cell colony formation in semi-solid agar system. T cell lines (STIL-3) that produce IL-3 were established from the spleen of these mice, with surface markers of helper (STIL-3D), suppressor (STIL-3C) and non-H, non-S (STIL-3A) T cells. An ATL patient was found to show a similar syndrome with granulocytosis and high level of IL-3 in the serum as L8313. IL-2 dependent helper T cell line\uff08HIL-3) that produces human IL-3 was established from the bone marrow of the patient. This IL-3 acts not only on human marrow cells but also on mouse marrow cells as target, which is completely different from previously reported human IL-3. Our human IL-3 appears to be native and innate IL-3. Soft-agar system was applied for assay of IL-3 activity. This agar system supports 100% pure mast cell colony-formation with high seeding efficiency, when marrow cells were cultured with IL-3 for 2-3 weeks, thus providing a useful technique for quantification of IL-3 activity.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "138469", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Mori, Kazuhiro J."}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u68ee, \u548c\u535a"}], "nameIdentifiers": [{"nameIdentifier": "138468", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(5)_354-363.pdf", "filesize": [{"value": "2.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2400000.0, "url": {"label": "103(5)_354-363.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22910/files/103(5)_354-363.pdf"}, "version_id": "2fdeefed-283d-400e-a6d9-2020f508ef51"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "IL-3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "T-cell leukemia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "granulocytosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mast cell colony-formation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-3 producing cell lines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u9846\u7c92\u7403\u5897\u591a\u75c7", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30de\u30b9\u30c8\u7d30\u80de\u30b3\u30ed\u30cb\u30fc", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-3\u7523\u751f\u7d30\u80de", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "4) IL-3 \u30de\u30a6\u30b9\u304a\u3088\u3073\u30d2\u30c8IL-3\u7523\u751fT\u7d30\u80de\u682a\u306e\u6a39\u7acb\u3068\u30de\u30b9\u30c8\u7d30\u80de\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u6cd5\u3092\u7528\u3044\u305f\u6d3b\u6027\u6e2c\u5b9a(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 Growth Factor\u306e\u57fa\u790e\u3068\u81e8\u5e8a, \u7b2c434\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "4) IL-3 \u30de\u30a6\u30b9\u304a\u3088\u3073\u30d2\u30c8IL-3\u7523\u751fT\u7d30\u80de\u682a\u306e\u6a39\u7acb\u3068\u30de\u30b9\u30c8\u7d30\u80de\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u6cd5\u3092\u7528\u3044\u305f\u6d3b\u6027\u6e2c\u5b9a(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 Growth Factor\u306e\u57fa\u790e\u3068\u81e8\u5e8a, \u7b2c434\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"}, {"subitem_title": "4) IL-3 \u30de\u30a6\u30b9\u304a\u3088\u3073\u30d2\u30c8IL-3\u7523\u751fT\u7d30\u80de\u682a\u306e\u6a39\u7acb\u3068\u30de\u30b9\u30c8\u7d30\u80de\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u6cd5\u3092\u7528\u3044\u305f\u6d3b\u6027\u6e2c\u5b9a(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 Growth Factor\u306e\u57fa\u790e\u3068\u81e8\u5e8a, \u7b2c434\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1210"], "permalink_uri": "http://hdl.handle.net/10191/41253", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-04-11"}, "publish_date": "2016-04-11", "publish_status": "0", "recid": "22910", "relation": {}, "relation_version_is_last": true, "title": ["4) IL-3 \u30de\u30a6\u30b9\u304a\u3088\u3073\u30d2\u30c8IL-3\u7523\u751fT\u7d30\u80de\u682a\u306e\u6a39\u7acb\u3068\u30de\u30b9\u30c8\u7d30\u80de\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u6cd5\u3092\u7528\u3044\u305f\u6d3b\u6027\u6e2c\u5b9a(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 Growth Factor\u306e\u57fa\u790e\u3068\u81e8\u5e8a, \u7b2c434\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"], "weko_shared_id": null}