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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第103巻第5号

4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)

http://hdl.handle.net/10191/41253
http://hdl.handle.net/10191/41253
48d25506-62bb-4bf1-ab88-f7403a4f69c7
名前 / ファイル ライセンス アクション
103(5)_354-363.pdf 103(5)_354-363.pdf (2.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-04-11
タイトル
タイトル 4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)
タイトル
言語 en
タイトル 4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 IL-3
キーワード
主題Scheme Other
主題 T-cell leukemia
キーワード
主題Scheme Other
主題 granulocytosis
キーワード
主題Scheme Other
主題 mast cell colony-formation
キーワード
主題Scheme Other
主題 IL-3 producing cell lines
キーワード
主題Scheme Other
主題 インターロイキン-3
キーワード
主題Scheme Other
主題 顆粒球増多症
キーワード
主題Scheme Other
主題 マスト細胞コロニー
キーワード
主題Scheme Other
主題 IL-3産生細胞
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Establishment of mouse and human IL-3 producing T cell lines and a specific technique for quantification of IL-3 activity by mast cell-colony formation in soft agar.(Recent Advances in Research on the Cell Growth Factors)
著者 森, 和博

× 森, 和博

WEKO 138468

森, 和博

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著者別名
識別子 138469
識別子Scheme WEKO
姓名 Mori, Kazuhiro J.
抄録
内容記述タイプ Abstract
内容記述 Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and increase in hemopoietic stem cells and progenitors in the spleen. Serum and spleen-conditioned medium of the mouse induced CFU-mix, BFU-E and GM-CFC derived colonies, and supported growth of IL-3 dependent cell lines, FDC-P2 and DA-1. They also induced mast cell colony formation in semi-solid agar system. T cell lines (STIL-3) that produce IL-3 were established from the spleen of these mice, with surface markers of helper (STIL-3D), suppressor (STIL-3C) and non-H, non-S (STIL-3A) T cells. An ATL patient was found to show a similar syndrome with granulocytosis and high level of IL-3 in the serum as L8313. IL-2 dependent helper T cell line(HIL-3) that produces human IL-3 was established from the bone marrow of the patient. This IL-3 acts not only on human marrow cells but also on mouse marrow cells as target, which is completely different from previously reported human IL-3. Our human IL-3 appears to be native and innate IL-3. Soft-agar system was applied for assay of IL-3 activity. This agar system supports 100% pure mast cell colony-formation with high seeding efficiency, when marrow cells were cultured with IL-3 for 2-3 weeks, thus providing a useful technique for quantification of IL-3 activity.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 103, 号 5, p. 354-363, 発行日 1989-05
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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