WEKO3
アイテム
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4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)
http://hdl.handle.net/10191/41253
http://hdl.handle.net/10191/4125348d25506-62bb-4bf1-ab88-f7403a4f69c7
名前 / ファイル | ライセンス | アクション |
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103(5)_354-363.pdf (2.4 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-04-11 | |||||
タイトル | ||||||
タイトル | 4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | IL-3 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | T-cell leukemia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | granulocytosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mast cell colony-formation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | IL-3 producing cell lines | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | インターロイキン-3 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 顆粒球増多症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | マスト細胞コロニー | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | IL-3産生細胞 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Establishment of mouse and human IL-3 producing T cell lines and a specific technique for quantification of IL-3 activity by mast cell-colony formation in soft agar.(Recent Advances in Research on the Cell Growth Factors) | |||||
著者 |
森, 和博
× 森, 和博 |
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著者別名 | ||||||
識別子 | 138469 | |||||
識別子Scheme | WEKO | |||||
姓名 | Mori, Kazuhiro J. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and increase in hemopoietic stem cells and progenitors in the spleen. Serum and spleen-conditioned medium of the mouse induced CFU-mix, BFU-E and GM-CFC derived colonies, and supported growth of IL-3 dependent cell lines, FDC-P2 and DA-1. They also induced mast cell colony formation in semi-solid agar system. T cell lines (STIL-3) that produce IL-3 were established from the spleen of these mice, with surface markers of helper (STIL-3D), suppressor (STIL-3C) and non-H, non-S (STIL-3A) T cells. An ATL patient was found to show a similar syndrome with granulocytosis and high level of IL-3 in the serum as L8313. IL-2 dependent helper T cell line(HIL-3) that produces human IL-3 was established from the bone marrow of the patient. This IL-3 acts not only on human marrow cells but also on mouse marrow cells as target, which is completely different from previously reported human IL-3. Our human IL-3 appears to be native and innate IL-3. Soft-agar system was applied for assay of IL-3 activity. This agar system supports 100% pure mast cell colony-formation with high seeding efficiency, when marrow cells were cultured with IL-3 for 2-3 weeks, thus providing a useful technique for quantification of IL-3 activity. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 103, 号 5, p. 354-363, 発行日 1989-05 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |