{"_buckets": {"deposit": "6cddec24-60ba-47ea-96d7-dd15faf9e36e"}, "_deposit": {"id": "22910", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22910"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022910", "sets": ["456", "1210"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Establishment of mouse and human IL-3 producing T cell lines and a specific technique for quantification of IL-3 activity by mast cell-colony formation in soft agar.(Recent Advances in Research on the Cell Growth Factors)"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "363", "bibliographicPageStart": "354", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and increase in hemopoietic stem cells and progenitors in the spleen. Serum and spleen-conditioned medium of the mouse induced CFU-mix, BFU-E and GM-CFC derived colonies, and supported growth of IL-3 dependent cell lines, FDC-P2 and DA-1. They also induced mast cell colony formation in semi-solid agar system. T cell lines (STIL-3) that produce IL-3 were established from the spleen of these mice, with surface markers of helper (STIL-3D), suppressor (STIL-3C) and non-H, non-S (STIL-3A) T cells. An ATL patient was found to show a similar syndrome with granulocytosis and high level of IL-3 in the serum as L8313. IL-2 dependent helper T cell line（HIL-3) that produces human IL-3 was established from the bone marrow of the patient. This IL-3 acts not only on human marrow cells but also on mouse marrow cells as target, which is completely different from previously reported human IL-3. Our human IL-3 appears to be native and innate IL-3. Soft-agar system was applied for assay of IL-3 activity. This agar system supports 100% pure mast cell colony-formation with high seeding efficiency, when marrow cells were cultured with IL-3 for 2-3 weeks, thus providing a useful technique for quantification of IL-3 activity.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "138469", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Mori, Kazuhiro J."}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "森, 和博"}], "nameIdentifiers": [{"nameIdentifier": "138468", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(5)_354-363.pdf", "filesize": [{"value": "2.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2400000.0, "url": {"label": "103(5)_354-363.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22910/files/103(5)_354-363.pdf"}, "version_id": "2fdeefed-283d-400e-a6d9-2020f508ef51"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "IL-3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "T-cell leukemia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "granulocytosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mast cell colony-formation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-3 producing cell lines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "インターロイキン-3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "顆粒球増多症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "マスト細胞コロニー", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-3産生細胞", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)"}, {"subitem_title": "4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1210"], "permalink_uri": "http://hdl.handle.net/10191/41253", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-04-11"}, "publish_date": "2016-04-11", "publish_status": "0", "recid": "22910", "relation": {}, "relation_version_is_last": true, "title": ["4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)"], "weko_shared_id": null}