{"created":"2021-03-01T06:28:06.769197+00:00","id":22910,"links":{},"metadata":{"_buckets":{"deposit":"6cddec24-60ba-47ea-96d7-dd15faf9e36e"},"_deposit":{"id":"22910","owners":[],"pid":{"revision_id":0,"type":"depid","value":"22910"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00022910","sets":["453:456","471:537:538:1210"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Establishment of mouse and human IL-3 producing T cell lines and a specific technique for quantification of IL-3 activity by mast cell-colony formation in soft agar.(Recent Advances in Research on the Cell Growth Factors)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1989-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"363","bibliographicPageStart":"354","bibliographicVolumeNumber":"103","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and increase in hemopoietic stem cells and progenitors in the spleen. Serum and spleen-conditioned medium of the mouse induced CFU-mix, BFU-E and GM-CFC derived colonies, and supported growth of IL-3 dependent cell lines, FDC-P2 and DA-1. They also induced mast cell colony formation in semi-solid agar system. T cell lines (STIL-3) that produce IL-3 were established from the spleen of these mice, with surface markers of helper (STIL-3D), suppressor (STIL-3C) and non-H, non-S (STIL-3A) T cells. An ATL patient was found to show a similar syndrome with granulocytosis and high level of IL-3 in the serum as L8313. IL-2 dependent helper T cell line（HIL-3) that produces human IL-3 was established from the bone marrow of the patient. This IL-3 acts not only on human marrow cells but also on mouse marrow cells as target, which is completely different from previously reported human IL-3. Our human IL-3 appears to be native and innate IL-3. Soft-agar system was applied for assay of IL-3 activity. This agar system supports 100% pure mast cell colony-formation with high seeding efficiency, when marrow cells were cultured with IL-3 for 2-3 weeks, thus providing a useful technique for quantification of IL-3 activity.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"138469","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Mori, Kazuhiro J."}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森, 和博"}],"nameIdentifiers":[{"nameIdentifier":"138468","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"103(5)_354-363.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"103(5)_354-363.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/22910/files/103(5)_354-363.pdf"},"version_id":"2fdeefed-283d-400e-a6d9-2020f508ef51"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"IL-3","subitem_subject_scheme":"Other"},{"subitem_subject":"T-cell leukemia","subitem_subject_scheme":"Other"},{"subitem_subject":"granulocytosis","subitem_subject_scheme":"Other"},{"subitem_subject":"mast cell colony-formation","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-3 producing cell lines","subitem_subject_scheme":"Other"},{"subitem_subject":"インターロイキン-3","subitem_subject_scheme":"Other"},{"subitem_subject":"顆粒球増多症","subitem_subject_scheme":"Other"},{"subitem_subject":"マスト細胞コロニー","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-3産生細胞","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)"},{"subitem_title":"4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1210"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-11"},"publish_date":"2016-04-11","publish_status":"0","recid":"22910","relation_version_is_last":true,"title":["4) IL-3 マウスおよびヒトIL-3産生T細胞株の樹立とマスト細胞コロニー形成法を用いた活性測定(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:52:40.709982+00:00"}