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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第104巻第7号

成人急性リンパ性白血病の治療(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)

http://hdl.handle.net/10191/34471
http://hdl.handle.net/10191/34471
d5dda21e-34b8-42af-bbc3-570679147a5c
名前 / ファイル ライセンス アクション
104(7)_546-551.pdf 104(7)_546-551.pdf (797.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-11-16
タイトル
タイトル 成人急性リンパ性白血病の治療(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)
タイトル
言語 en
タイトル 成人急性リンパ性白血病の治療(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)
言語
言語 jpn
キーワード
主題Scheme Other
主題 Adult ALL
キーワード
主題Scheme Other
主題 treatment
キーワード
主題Scheme Other
主題 L-series
キーワード
主題Scheme Other
主題 成人急性リンパ性白血病
キーワード
主題Scheme Other
主題 治療法の進歩
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Recent advances in the treatment of adult ALL(20th Meeting of the Niigata Society of Hematologic Neoplasm The Ten-year Anniversary Symposium : Progress in Hematologic Neoplasm over the Ten Years)
著者 林, 直樹

× 林, 直樹

WEKO 134749

林, 直樹

Search repository
荒川, 正昭

× 荒川, 正昭

WEKO 134750

荒川, 正昭

Search repository
著者別名
識別子 134751
識別子Scheme WEKO
姓名 Hayashi, Naoki
著者別名
識別子 134752
識別子Scheme WEKO
姓名 Arakawa, Masaaki
抄録
内容記述タイプ Abstract
内容記述 The treatment of adult acute lymphocytic leukemia (ALL) has been still unsatisfactory because of high relapsing rate after complete remission (CR) and easy acquirement of multiple drug resistance, although that of childhood ALL has been improved remarkably. In order to keep long-term CR, more intensive induction, consolidation and maintenance therapies have to be introduced. Based on this therapeutic concept, Memorial Sloan Kettering's group has introduced L-series protocol and reported favorable clinical results. We have tried modified L-10M protocol as our standard regimen since 1985. All 5 patients treated so far have achieved CR, but relapse in central nerve system (CNS) was found in 2 cases after cessation of intrathecal methotrexate injection, which suggested the importance of prophylactic treatment for CNS leukemia. In addition to the progress of chemotherapeutic strategy, the development of diagnostic methods, more advanced supportive therapies and bone marrow transplantation shoud be considered for improving clinical results. Finally, attempts for developing new chemotherapeutic agents, new treatment programs and novel immunotherapy (application of biological response modifiers etc) will be necessary for getting better clinical results in adult ALL.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 104, 号 7, p. 546-551, 発行日 1990-07
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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