{"_buckets": {"deposit": "b6384580-6bcc-4951-a2b2-e0fd7d33a846"}, "_deposit": {"id": "22173", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22173"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022173"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Recent advances in the treatment of adult ALL(20th Meeting of the Niigata Society of Hematologic Neoplasm The Ten-year Anniversary Symposium : Progress in Hematologic Neoplasm over the Ten Years)"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "551", "bibliographicPageStart": "546", "bibliographicVolumeNumber": "104", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The treatment of adult acute lymphocytic leukemia \uff08ALL\uff09 has been still unsatisfactory because of high relapsing rate after complete remission \uff08CR\uff09 and easy acquirement of multiple drug resistance, although that of childhood ALL has been improved remarkably. In order to keep long-term CR, more intensive induction, consolidation and maintenance therapies have to be introduced. Based on this therapeutic concept, Memorial Sloan Kettering\u0027s group has introduced L-series protocol and reported favorable clinical results. We have tried modified L-10M protocol as our standard regimen since 1985. All 5 patients treated so far have achieved CR, but relapse in central nerve system \uff08CNS\uff09 was found in 2 cases after cessation of intrathecal methotrexate injection, which suggested the importance of prophylactic treatment for CNS leukemia. In addition to the progress of chemotherapeutic strategy, the development of diagnostic methods, more advanced supportive therapies and bone marrow transplantation shoud be considered for improving clinical results. Finally, attempts for developing new chemotherapeutic agents, new treatment programs and novel immunotherapy \uff08application of biological response modifiers etc\uff09 will be necessary for getting better clinical results in adult ALL.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "134751", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hayashi, Naoki"}]}, {"nameIdentifiers": [{"nameIdentifier": "134752", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Arakawa, Masaaki"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u6797, \u76f4\u6a39"}], "nameIdentifiers": [{"nameIdentifier": "134749", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "\u8352\u5ddd, \u6b63\u662d"}], "nameIdentifiers": [{"nameIdentifier": "134750", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "104(7)_546-551.pdf", "filesize": [{"value": "797.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 797300.0, "url": {"label": "104(7)_546-551.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22173/files/104(7)_546-551.pdf"}, "version_id": "907e960a-bca7-43e6-8262-593915689596"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Adult ALL", "subitem_subject_scheme": "Other"}, {"subitem_subject": "treatment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "L-series", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6210\u4eba\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6cbb\u7642\u6cd5\u306e\u9032\u6b69", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u6210\u4eba\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u6cbb\u7642\uff08\u7b2c20\u56de\u65b0\u6f5f\u9020\u8840\u5668\u816b\u760d\u7814\u7a76\u4f1a\u5341\u5468\u5e74\u8a18\u5ff5\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 : \u9020\u8840\u5668\u816b\u760d\u5341\u5e74\u306e\u6b69\u307f\uff09", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u6210\u4eba\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u6cbb\u7642\uff08\u7b2c20\u56de\u65b0\u6f5f\u9020\u8840\u5668\u816b\u760d\u7814\u7a76\u4f1a\u5341\u5468\u5e74\u8a18\u5ff5\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 : \u9020\u8840\u5668\u816b\u760d\u5341\u5e74\u306e\u6b69\u307f\uff09"}, {"subitem_title": "\u6210\u4eba\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u6cbb\u7642\uff08\u7b2c20\u56de\u65b0\u6f5f\u9020\u8840\u5668\u816b\u760d\u7814\u7a76\u4f1a\u5341\u5468\u5e74\u8a18\u5ff5\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 : \u9020\u8840\u5668\u816b\u760d\u5341\u5e74\u306e\u6b69\u307f\uff09", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1196"], "permalink_uri": "http://hdl.handle.net/10191/34471", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-11-16"}, "publish_date": "2015-11-16", "publish_status": "0", "recid": "22173", "relation": {}, "relation_version_is_last": true, "title": ["\u6210\u4eba\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u6cbb\u7642\uff08\u7b2c20\u56de\u65b0\u6f5f\u9020\u8840\u5668\u816b\u760d\u7814\u7a76\u4f1a\u5341\u5468\u5e74\u8a18\u5ff5\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 : \u9020\u8840\u5668\u816b\u760d\u5341\u5e74\u306e\u6b69\u307f\uff09"], "weko_shared_id": null}