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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第104巻第10号

Lyt-2 陽性細胞によるMHCクラスI移植細胞対宿主反応(GVHR)はL3T4陽性細胞によるMHCクラスII GVHRを制御する

http://hdl.handle.net/10191/34971
http://hdl.handle.net/10191/34971
896f977b-4ddb-4332-8e04-220d58774dab
名前 / ファイル ライセンス アクション
104(10)_845-851.pdf 104(10)_845-851.pdf (1.8 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-12-04
タイトル
タイトル Lyt-2 陽性細胞によるMHCクラスI移植細胞対宿主反応(GVHR)はL3T4陽性細胞によるMHCクラスII GVHRを制御する
タイトル
言語 en
タイトル Lyt-2 陽性細胞によるMHCクラスI移植細胞対宿主反応(GVHR)はL3T4陽性細胞によるMHCクラスII GVHRを制御する
言語
言語 jpn
キーワード
主題Scheme Other
主題 GVHR
キーワード
主題Scheme Other
主題 MHC class I
キーワード
主題Scheme Other
主題 MHC class II
キーワード
主題Scheme Other
主題 Lyt-2^+ cells
キーワード
主題Scheme Other
主題 L3T4^+ cells
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Lyt-2^+ T cells Modify GVHR Induced by L3T4^+ T cells in MHC Class I Plus II-Disparate Hosts
著者 五十嵐, 美徳

× 五十嵐, 美徳

WEKO 133580

五十嵐, 美徳

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著者別名
識別子 133581
識別子Scheme WEKO
姓名 Ikarashi, Yoshinori
抄録
内容記述タイプ Abstract
内容記述 When B6 T cells are injected into unirradiated (bm1×bm12) F1 hosts, graft-versushost reactions (GVHR) are induced which are classified into two types. The one is MHC class II GVHR induced by L3T4^+ cells and the other is MHC class I GVHR by Lyt- 2^+ cells. When both L3T4^+ and Lyt-2^+ cells were injected into (bm1×bm12) F1 mice, a strong immunodeficient state was induced. Responsiveness to mitogens was abrogated. Class II GVHR showing polyclonal B cell activation was markedly suppressed by inducing class I GVHR simultaneously. The spleen cells of hosts with class II plus class I GVHR showed a marked decrease in IgM^+ cells and an increase in Thy-1^+ Lyt-2^+ cells by flowcytometric analysis. The latter population might function as suppressor and/or cytotoxic cells against host MHC antigens. Significance of the phenomena in the development of autoimmune disease is discussed.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 104, 号 10, p. 845-851, 発行日 1990-10
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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