{"_buckets": {"deposit": "ed6bc063-dcf4-486c-a5df-26309bf093b7"}, "_deposit": {"id": "21953", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "21953"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00021953"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Lyt-2^+ T cells Modify GVHR Induced by L3T4^+ T cells in MHC Class I Plus II-Disparate Hosts"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "851", "bibliographicPageStart": "845", "bibliographicVolumeNumber": "104", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "When B6 T cells are injected into unirradiated (bm1\u00d7bm12) F1 hosts, graft-versushost reactions (GVHR) are induced which are classified into two types. The one is MHC class II GVHR induced by L3T4^+ cells and the other is MHC class I GVHR by Lyt- 2^+ cells. When both L3T4^+ and Lyt-2^+ cells were injected into (bm1\u00d7bm12) F1 mice, a strong immunodeficient state was induced. Responsiveness to mitogens was abrogated. Class II GVHR showing polyclonal B cell activation was markedly suppressed by inducing class I GVHR simultaneously. The spleen cells of hosts with class II plus class I GVHR showed a marked decrease in IgM^+ cells and an increase in Thy-1^+ Lyt-2^+ cells by flowcytometric analysis. The latter population might function as suppressor and/or cytotoxic cells against host MHC antigens. Significance of the phenomena in the development of autoimmune disease is discussed.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "133581", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ikarashi, Yoshinori"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u4e94\u5341\u5d50, \u7f8e\u5fb3"}], "nameIdentifiers": [{"nameIdentifier": "133580", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "104(10)_845-851.pdf", "filesize": [{"value": "1.8 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1800000.0, "url": {"label": "104(10)_845-851.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/21953/files/104(10)_845-851.pdf"}, "version_id": "ab1fc298-a3d3-4525-a7fb-d3583b6d495b"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "GVHR", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MHC class I", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MHC class II", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Lyt-2^+ cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "L3T4^+ cells", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Lyt-2 \u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9I\u79fb\u690d\u7d30\u80de\u5bfe\u5bbf\u4e3b\u53cd\u5fdc(GVHR)\u306fL3T4\u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9II GVHR\u3092\u5236\u5fa1\u3059\u308b", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Lyt-2 \u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9I\u79fb\u690d\u7d30\u80de\u5bfe\u5bbf\u4e3b\u53cd\u5fdc(GVHR)\u306fL3T4\u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9II GVHR\u3092\u5236\u5fa1\u3059\u308b"}, {"subitem_title": "Lyt-2 \u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9I\u79fb\u690d\u7d30\u80de\u5bfe\u5bbf\u4e3b\u53cd\u5fdc(GVHR)\u306fL3T4\u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9II GVHR\u3092\u5236\u5fa1\u3059\u308b", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1193"], "permalink_uri": "http://hdl.handle.net/10191/34971", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-12-04"}, "publish_date": "2015-12-04", "publish_status": "0", "recid": "21953", "relation": {}, "relation_version_is_last": true, "title": ["Lyt-2 \u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9I\u79fb\u690d\u7d30\u80de\u5bfe\u5bbf\u4e3b\u53cd\u5fdc(GVHR)\u306fL3T4\u967d\u6027\u7d30\u80de\u306b\u3088\u308bMHC\u30af\u30e9\u30b9II GVHR\u3092\u5236\u5fa1\u3059\u308b"], "weko_shared_id": null}