{"_buckets": {"deposit": "c3f0ba2d-3a2b-42f8-a387-89bf264cbb44"}, "_deposit": {"id": "21634", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "21634"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00021634"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "New Drugs for DIC"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "108", "bibliographicPageStart": "103", "bibliographicVolumeNumber": "105", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Heparin has long been used for disseminated intravascular coagulation (DIC), but recently some new drugs have become available for DIC. The concentrate of Antithrombin III, which is a physiological protease inhibitor, is used in combination with heparin. Low molecular weight heparin (LMWH) with molecular weight of about 4000\uff5e6000 has more anti-X_a activity than anti-IIa activity. For this reason, LMWH has an anticoagulant activity with a low bleeding risk. Synthetic protease inhibitors (eg. FUTHAN) directly inhibit several protease activities in the absence of antithrombin III. Activated protein C inactivates V_a and VIII_a with protein S as a cofactor, and inhibits plasminogen activator inhibitor. Its concentrate may be effective for patients with DIC especially caused by endotoxicemia. DIC is heterogeneous in coagulation-fibrinolysis balance and is associated with various diseases, so we must choose suitable drugs for individual patients.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "132009", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Tatewaki, Wataru"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u5e2f\u5200, \u4e98"}], "nameIdentifiers": [{"nameIdentifier": "132008", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "105(2)_103-108.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "105(2)_103-108.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/21634/files/105(2)_103-108.pdf"}, "version_id": "89d1954a-09b9-46fd-be64-69866c11483e"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "low molecular weight heparin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "synthetic protease inhibitor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "activated protein C", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u4f4e\u5206\u5b50\u30d8\u30d1\u30ea\u30f3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u5408\u6210\u86cb\u767d\u5206\u89e3\u9175\u7d20\u963b\u5bb3\u5264", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6d3b\u6027\u5316\u30d7\u30ed\u30c6\u30a4\u30f3C", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "5) DIC\u306e\u65b0\u3057\u3044\u6cbb\u7642\u85acF(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 DIC-\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u6700\u8fd1\u306e\u52d5\u5411, \u7b2c457\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "5) DIC\u306e\u65b0\u3057\u3044\u6cbb\u7642\u85acF(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 DIC-\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u6700\u8fd1\u306e\u52d5\u5411, \u7b2c457\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"}, {"subitem_title": "5) DIC\u306e\u65b0\u3057\u3044\u6cbb\u7642\u85acF(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 DIC-\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u6700\u8fd1\u306e\u52d5\u5411, \u7b2c457\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1189"], "permalink_uri": "http://hdl.handle.net/10191/38609", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-02-22"}, "publish_date": "2016-02-22", "publish_status": "0", "recid": "21634", "relation": {}, "relation_version_is_last": true, "title": ["5) DIC\u306e\u65b0\u3057\u3044\u6cbb\u7642\u85acF(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 DIC-\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u6700\u8fd1\u306e\u52d5\u5411, \u7b2c457\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"], "weko_shared_id": null}