{"created":"2021-03-01T06:26:42.419097+00:00","id":21634,"links":{},"metadata":{"_buckets":{"deposit":"c3f0ba2d-3a2b-42f8-a387-89bf264cbb44"},"_deposit":{"id":"21634","owners":[],"pid":{"revision_id":0,"type":"depid","value":"21634"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00021634","sets":["453:456","471:537:538:1189"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"New Drugs for DIC"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"108","bibliographicPageStart":"103","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Heparin has long been used for disseminated intravascular coagulation (DIC), but recently some new drugs have become available for DIC. The concentrate of Antithrombin III, which is a physiological protease inhibitor, is used in combination with heparin. Low molecular weight heparin (LMWH) with molecular weight of about 4000～6000 has more anti-X_a activity than anti-IIa activity. For this reason, LMWH has an anticoagulant activity with a low bleeding risk. Synthetic protease inhibitors (eg. FUTHAN) directly inhibit several protease activities in the absence of antithrombin III. Activated protein C inactivates V_a and VIII_a with protein S as a cofactor, and inhibits plasminogen activator inhibitor. Its concentrate may be effective for patients with DIC especially caused by endotoxicemia. DIC is heterogeneous in coagulation-fibrinolysis balance and is associated with various diseases, so we must choose suitable drugs for individual patients.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"132009","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tatewaki, Wataru"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"帯刀, 亘"}],"nameIdentifiers":[{"nameIdentifier":"132008","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"105(2)_103-108.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"105(2)_103-108.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/21634/files/105(2)_103-108.pdf"},"version_id":"89d1954a-09b9-46fd-be64-69866c11483e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"low molecular weight heparin","subitem_subject_scheme":"Other"},{"subitem_subject":"synthetic protease inhibitor","subitem_subject_scheme":"Other"},{"subitem_subject":"activated protein C","subitem_subject_scheme":"Other"},{"subitem_subject":"低分子ヘパリン","subitem_subject_scheme":"Other"},{"subitem_subject":"合成蛋白分解酵素阻害剤","subitem_subject_scheme":"Other"},{"subitem_subject":"活性化プロテインC","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"5) DICの新しい治療薬F(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"5) DICの新しい治療薬F(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)"},{"subitem_title":"5) DICの新しい治療薬F(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1189"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-22"},"publish_date":"2016-02-22","publish_status":"0","recid":"21634","relation_version_is_last":true,"title":["5) DICの新しい治療薬F(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:52:07.418742+00:00"}