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FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines
http://hdl.handle.net/10191/1184
http://hdl.handle.net/10191/1184334bbd9a-cae9-4ec2-a7ff-a3e34dce036d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
24_0012.pdf (1.0 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-04-23 | |||||
| タイトル | ||||||
| タイトル | FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | CD22 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | FcεR1 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | B cells | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | basophils | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hematopoiesis | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 著者 |
Toba, Ken
× Toba, Ken× Hanawa, Haruo× Sakaue, Minori× Yoshida, Kaori× Itoh, Hiromi× Tsuchiyama, Junjiro× Maruyama, Soichi× Narita, Miwako× Takahashi, Masuhiro× Watanabe, Ken-Ichi× Aizawa, Yoshifusa |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 7266 | |||||
| 姓名 | 鳥羽, 健 | |||||
| 言語 | ja | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature basophil granulocytes. We then investigated the expression of CD22 and other B cell- and basophil-related molecules in 25 human acute leukemia cell lines to find the phenotype of the virtual common progenitor of B- and myeloid lineage. Surface and cytoplasmic expressions of antigens were analyzed using a flow cytometer and an essential antibody-panel used for diagnosing acute leukemia as well as cytokine receptors and basophil-related enzymes. Messenger RNA expression of FcεR1 and CD22 was also analyzed. Peroxidase-positive and -negative myeloid leukemias showed eosinophil- and basophil-type expression of enzymes, respectively. Early myeloid and B-lineage cells expressed basically similar combinations of cytokine receptors and various combinations of mRNA listed above, while T-lineage cells did not. The virtual common progenitor of B- and myeloid lineage cells may be defined as immature cells simultaneously expressing B- and basophil phenotypes. | |||||
| 書誌情報 |
Leukemia Research en : Leukemia Research 巻 27, 号 2, p. 173-182, 発行日 2003-02 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0145-2126 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00716755 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | http://doi.org/10.1016/s0145-2126(02)00086-3 | |||||
| 権利 | ||||||
| 権利情報 | Elsevier Ltd | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 著者版フラグ | ||||||
| 値 | author | |||||
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Cite as
Toba, Ken, Hanawa, Haruo, Sakaue, Minori, Yoshida, Kaori, Itoh, Hiromi, Tsuchiyama, Junjiro, Maruyama, Soichi, Narita, Miwako, Takahashi, Masuhiro, Watanabe, Ken-Ichi, Aizawa, Yoshifusa, 2003, FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines: Elsevier, 173–182 p.
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