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FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines
http://hdl.handle.net/10191/1184
http://hdl.handle.net/10191/1184334bbd9a-cae9-4ec2-a7ff-a3e34dce036d
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-04-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD22 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | FcεR1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | B cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | basophils | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hematopoiesis | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Toba, Ken
× Toba, Ken× Hanawa, Haruo× Sakaue, Minori× Yoshida, Kaori× Itoh, Hiromi× Tsuchiyama, Junjiro× Maruyama, Soichi× Narita, Miwako× Takahashi, Masuhiro× Watanabe, Ken-Ichi× Aizawa, Yoshifusa |
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著者別名 | ||||||
識別子 | 7266 | |||||
識別子Scheme | WEKO | |||||
姓名 | 鳥羽, 健 | |||||
言語 | ja | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature basophil granulocytes. We then investigated the expression of CD22 and other B cell- and basophil-related molecules in 25 human acute leukemia cell lines to find the phenotype of the virtual common progenitor of B- and myeloid lineage. Surface and cytoplasmic expressions of antigens were analyzed using a flow cytometer and an essential antibody-panel used for diagnosing acute leukemia as well as cytokine receptors and basophil-related enzymes. Messenger RNA expression of FcεR1 and CD22 was also analyzed. Peroxidase-positive and -negative myeloid leukemias showed eosinophil- and basophil-type expression of enzymes, respectively. Early myeloid and B-lineage cells expressed basically similar combinations of cytokine receptors and various combinations of mRNA listed above, while T-lineage cells did not. The virtual common progenitor of B- and myeloid lineage cells may be defined as immature cells simultaneously expressing B- and basophil phenotypes. | |||||
書誌情報 |
Leukemia Research en : Leukemia Research 巻 27, 号 2, p. 173-182, 発行日 2003-02 |
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出版者 | ||||||
出版者 | Elsevier | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0145-2126 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00716755 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | http://doi.org/10.1016/s0145-2126(02)00086-3 | |||||
権利 | ||||||
権利情報 | Elsevier Ltd | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
著者版フラグ | ||||||
値 | author |