{"created":"2021-03-01T06:05:50.980017+00:00","id":2154,"links":{},"metadata":{"_buckets":{"deposit":"975c87db-e5fd-44b9-9b66-0b955bf15748"},"_deposit":{"id":"2154","owners":[],"pid":{"revision_id":0,"type":"depid","value":"2154"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00002154","sets":["453:454","482:483:484"]},"author_link":["7255","7256","7257","7258","7259","7260","7261","7262","7263","7264","7265","7266"],"control_number":"2154","item_1627363077551":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"182","bibliographicPageStart":"173","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Leukemia Research"},{"bibliographic_title":"Leukemia Research","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature basophil granulocytes. We then investigated the expression of CD22 and other B cell- and basophil-related molecules in 25 human acute leukemia cell lines to find the phenotype of the virtual common progenitor of B- and myeloid lineage. Surface and cytoplasmic expressions of antigens were analyzed using a flow cytometer and an essential antibody-panel used for diagnosing acute leukemia as well as cytokine receptors and basophil-related enzymes. Messenger RNA expression of FcεR1 and CD22 was also analyzed. Peroxidase-positive and -negative myeloid leukemias showed eosinophil- and basophil-type expression of enzymes, respectively. Early myeloid and B-lineage cells expressed basically similar combinations of cytokine receptors and various combinations of mRNA listed above, while T-lineage cells did not. The virtual common progenitor of B- and myeloid lineage cells may be defined as immature cells simultaneously expressing B- and basophil phenotypes.","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"7266","nameIdentifierScheme":"WEKO"}],"names":[{"name":"鳥羽, 健","nameLang":"ja"}]}]},"item_5_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_5_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://doi.org/10.1016/s0145-2126(02)00086-3","subitem_relation_type_select":"DOI"}}]},"item_5_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Elsevier Ltd"}]},"item_5_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00716755","subitem_source_identifier_type":"NCID"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0145-2126","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Toba, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7255","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hanawa, Haruo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7256","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakaue, Minori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7257","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, Kaori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7258","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Itoh, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7259","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuchiyama, Junjiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7260","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Maruyama, Soichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7261","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Narita, Miwako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7262","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Masuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7263","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Ken-Ichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7264","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aizawa, Yoshifusa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7265","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-29"}],"displaytype":"detail","filename":"24_0012.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"24_0012.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/2154/files/24_0012.pdf"},"version_id":"b91d49bb-fd34-46e8-8f97-883acbcc996d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CD22","subitem_subject_scheme":"Other"},{"subitem_subject":"FcεR1","subitem_subject_scheme":"Other"},{"subitem_subject":"B cells","subitem_subject_scheme":"Other"},{"subitem_subject":"basophils","subitem_subject_scheme":"Other"},{"subitem_subject":"hematopoiesis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines","subitem_title_language":"en"}]},"item_type_id":"5","owner":"1","path":["454","484"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-04-23"},"publish_date":"2007-04-23","publish_status":"0","recid":"2154","relation_version_is_last":true,"title":["FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-15T04:35:45.736554+00:00"}