@article{oai:niigata-u.repo.nii.ac.jp:00002154,
 author = {Toba, Ken and Hanawa, Haruo and Sakaue, Minori and Yoshida, Kaori and Itoh, Hiromi and Tsuchiyama, Junjiro and Maruyama, Soichi and Narita, Miwako and Takahashi, Masuhiro and Watanabe, Ken-Ichi and Aizawa, Yoshifusa},
 issue = {2},
 journal = {Leukemia Research, Leukemia Research},
 month = {Feb},
 note = {CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature basophil granulocytes. We then investigated the expression of CD22 and other B cell- and basophil-related molecules in 25 human acute leukemia cell lines to find the phenotype of the virtual common progenitor of B- and myeloid lineage. Surface and cytoplasmic expressions of antigens were analyzed using a flow cytometer and an essential antibody-panel used for diagnosing acute leukemia as well as cytokine receptors and basophil-related enzymes. Messenger RNA expression of FcεR1 and CD22 was also analyzed. Peroxidase-positive and -negative myeloid leukemias showed eosinophil- and basophil-type expression of enzymes, respectively. Early myeloid and B-lineage cells expressed basically similar combinations of cytokine receptors and various combinations of mRNA listed above, while T-lineage cells did not. The virtual common progenitor of B- and myeloid lineage cells may be defined as immature cells simultaneously expressing B- and basophil phenotypes.},
 pages = {173--182},
 title = {FcεRI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines},
 volume = {27},
 year = {2003}
}