{"_buckets": {"deposit": "37039e56-5c9f-40ed-9f5a-9b38667aef96"}, "_deposit": {"id": "20968", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20968"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00020968"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Syndrome of Inappropriate Secretion of TSH : Follow up of Two Reported Cases(Clinic of the Thyroid Disease)"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "370", "bibliographicPageStart": "359", "bibliographicVolumeNumber": "106", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "We report the results of follow up for 7 to 8 years in two cases reported with syndrome of inappropriate secretion of TSH (SITSH). One case was due to TSH producing pituitary tumor and another one generalized resistance to thyroid hormone. In the former patient, at follow-up for 6 years after improvement by transshenoidal adenomectomy and then with methimazol treatment, he had recurrent thyrotoxicosis due to excessive secretion of serum TSH and \u03b1 TSH with regrowth of pituitary tumor shown by MRI. Subcutaneous injection with 100\u03bcg of octreotide decreased the levels of TSH and \u03b1 TSH and produced strong nausea and vomiting. The subcutaneous injection with continuous and intermittent time (12.5\u03bcg/2 hours) by infusion pump, however, improved the serum levels and regrowth of the tumor, and then thyrotoxicosis without the side effects. At 10 months after the therapy, recurrent thyrotoxicosis ocurred and was improved by additional administration of methimazol. The latter patient has normal growth for 7 years. Characteristics of thyroid recptor in the fibroblast were similar to normal by immunostaining or Western blot method, and length of the erb A \u03b2 receptor gene was normal. The observation indicates that we need to follow up patient with SITSH for a long period.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "128738", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kamoi, Kyuzi"}]}, {"nameIdentifiers": [{"nameIdentifier": "128739", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nakamura, Hirotoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "128740", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Shimazu, Akira"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u9d28\u4e95, \u4e45\u53f8"}], "nameIdentifiers": [{"nameIdentifier": "128735", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "\u4e2d\u6751, \u6d69\u6dd1"}], "nameIdentifiers": [{"nameIdentifier": "128736", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "\u5cf6\u6d25, \u7ae0"}], "nameIdentifiers": [{"nameIdentifier": "128737", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "106(05)_359-370.pdf", "filesize": [{"value": "3.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 3100000.0, "url": {"label": "106(05)_359-370.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/20968/files/106(05)_359-370.pdf"}, "version_id": "c54c105e-9895-4661-996e-f4d02c86a94c"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Syndrome of inappropriate secretion of TSH", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TSH-producing pituitary tumor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Syndrome of thyroid hormone resistance", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TSH\u4e0d\u9069\u5207\u5206\u6ccc\u75c7\u5019\u7fa4", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TSH\u7523\u751f\u4e0b\u5782\u4f53\u816b\u760d", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u4e0d\u5fdc\u75c7", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "2) TSH\u4e0d\u9069\u5207\u5206\u6ccc\u75c7\u5019\u7fa4\u306e2\u4f8b(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u7532\u72b6\u817a\u75be\u60a3\u306e\u81e8\u5e8a, \u7b2c469\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "2) TSH\u4e0d\u9069\u5207\u5206\u6ccc\u75c7\u5019\u7fa4\u306e2\u4f8b(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u7532\u72b6\u817a\u75be\u60a3\u306e\u81e8\u5e8a, \u7b2c469\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"}, {"subitem_title": "2) TSH\u4e0d\u9069\u5207\u5206\u6ccc\u75c7\u5019\u7fa4\u306e2\u4f8b(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u7532\u72b6\u817a\u75be\u60a3\u306e\u81e8\u5e8a, \u7b2c469\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1174"], "permalink_uri": "http://hdl.handle.net/10191/39688", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-03-15"}, "publish_date": "2016-03-15", "publish_status": "0", "recid": "20968", "relation": {}, "relation_version_is_last": true, "title": ["2) TSH\u4e0d\u9069\u5207\u5206\u6ccc\u75c7\u5019\u7fa4\u306e2\u4f8b(\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u7532\u72b6\u817a\u75be\u60a3\u306e\u81e8\u5e8a, \u7b2c469\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a)"], "weko_shared_id": null}