{"created":"2021-03-01T06:25:58.366287+00:00","id":20968,"links":{},"metadata":{"_buckets":{"deposit":"37039e56-5c9f-40ed-9f5a-9b38667aef96"},"_deposit":{"id":"20968","owners":[],"pid":{"revision_id":0,"type":"depid","value":"20968"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00020968","sets":["453:456","471:537:538:1174"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Syndrome of Inappropriate Secretion of TSH : Follow up of Two Reported Cases(Clinic of the Thyroid Disease)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"370","bibliographicPageStart":"359","bibliographicVolumeNumber":"106","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report the results of follow up for 7 to 8 years in two cases reported with syndrome of inappropriate secretion of TSH (SITSH). One case was due to TSH producing pituitary tumor and another one generalized resistance to thyroid hormone. In the former patient, at follow-up for 6 years after improvement by transshenoidal adenomectomy and then with methimazol treatment, he had recurrent thyrotoxicosis due to excessive secretion of serum TSH and α TSH with regrowth of pituitary tumor shown by MRI. Subcutaneous injection with 100μg of octreotide decreased the levels of TSH and α TSH and produced strong nausea and vomiting. The subcutaneous injection with continuous and intermittent time (12.5μg/2 hours) by infusion pump, however, improved the serum levels and regrowth of the tumor, and then thyrotoxicosis without the side effects. At 10 months after the therapy, recurrent thyrotoxicosis ocurred and was improved by additional administration of methimazol. The latter patient has normal growth for 7 years. Characteristics of thyroid recptor in the fibroblast were similar to normal by immunostaining or Western blot method, and length of the erb A β receptor gene was normal. The observation indicates that we need to follow up patient with SITSH for a long period.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"128738","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kamoi, Kyuzi"}]},{"nameIdentifiers":[{"nameIdentifier":"128739","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakamura, Hirotoshi"}]},{"nameIdentifiers":[{"nameIdentifier":"128740","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shimazu, Akira"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鴨井, 久司"}],"nameIdentifiers":[{"nameIdentifier":"128735","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村, 浩淑"}],"nameIdentifiers":[{"nameIdentifier":"128736","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島津, 章"}],"nameIdentifiers":[{"nameIdentifier":"128737","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"106(05)_359-370.pdf","filesize":[{"value":"3.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"106(05)_359-370.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/20968/files/106(05)_359-370.pdf"},"version_id":"c54c105e-9895-4661-996e-f4d02c86a94c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Syndrome of inappropriate secretion of TSH","subitem_subject_scheme":"Other"},{"subitem_subject":"TSH-producing pituitary tumor","subitem_subject_scheme":"Other"},{"subitem_subject":"Syndrome of thyroid hormone resistance","subitem_subject_scheme":"Other"},{"subitem_subject":"TSH不適切分泌症候群","subitem_subject_scheme":"Other"},{"subitem_subject":"TSH産生下垂体腫瘍","subitem_subject_scheme":"Other"},{"subitem_subject":"甲状腺ホルモン不応症","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"2) TSH不適切分泌症候群の2例(シンポジウム 甲状腺疾患の臨床, 第469回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"2) TSH不適切分泌症候群の2例(シンポジウム 甲状腺疾患の臨床, 第469回新潟医学会)"},{"subitem_title":"2) TSH不適切分泌症候群の2例(シンポジウム 甲状腺疾患の臨床, 第469回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1174"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-03-15"},"publish_date":"2016-03-15","publish_status":"0","recid":"20968","relation_version_is_last":true,"title":["2) TSH不適切分泌症候群の2例(シンポジウム 甲状腺疾患の臨床, 第469回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:51:36.032174+00:00"}