WEKO3
アイテム
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CD56陽性T細胞の特徴
http://hdl.handle.net/10191/38259
http://hdl.handle.net/10191/382595a6dcf46-7636-4ecc-890a-d49a5c91336a
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-02-10 | |||||
タイトル | ||||||
タイトル | CD56陽性T細胞の特徴 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | CD56陽性T細胞の特徴 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD56 positive T cells in human | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | extrathymic T cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD56陽性T細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 胸腺外分化T細胞 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | CD56 Positive T Cells in Human : Characterization and Localization | |||||
著者 |
橋本, 誠雄
× 橋本, 誠雄 |
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著者別名 | ||||||
識別子 | 120561 | |||||
識別子Scheme | WEKO | |||||
姓名 | Hashimoto, Shigeo | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In a series of recent studies, extrathymic T cell differentiation in mice has been reported. These T cells may be more primitive than that of thymic origin. Since they carry self reactive forbidden clones, it could be benefical for elimenating their own atypical cells. They express IL-2Rβ similar to NK cells, containing CD4 or CD8 double negative cells. Their morphology is large granular lymphocyte (LGL). This study is to elucidate the possibility that CD56 positive T cells with a morphology of LGL are the counterpart of extrathymic T cells in human. CD56 positive T cells were abundant in the liver comparing in peripheral blood from same donor. The phenotype of T cells in the liver mononuclear cells (MNC), CD56 positive T cells had considerably higher proportion of TCR-γδ aquisition, and CD4, CD8 double negative population were also existed in one of the case who had high population of CD56 positive T cells. While CD56 positive cells were absent in the thymus. CD56 positive T cells were able to proliferate in serum-rich medium condition supplemented with IL-2. CD56 positive T cells were also harvested from bone marrow cells in a liquid culture without thymic environment. These results described above and similarities of the extrathymic T cells in mice, strongly indicate the possibility that CD56 positive T cells is a counterpart of extrathymic T cells in humans. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 108, 号 5, p. 358-366, 発行日 1994-05 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |