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CD56陽性T細胞の特徴
http://hdl.handle.net/10191/38259
http://hdl.handle.net/10191/382595a6dcf46-7636-4ecc-890a-d49a5c91336a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
108(5)_358-366.pdf (1.7 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-02-10 | |||||
| タイトル | ||||||
| タイトル | CD56陽性T細胞の特徴 | |||||
| タイトル | ||||||
| タイトル | CD56陽性T細胞の特徴 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | CD56 positive T cells in human | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | extrathymic T cells | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | CD56陽性T細胞 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 胸腺外分化T細胞 | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | CD56 Positive T Cells in Human : Characterization and Localization | |||||
| 著者 |
橋本, 誠雄
× 橋本, 誠雄 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 120561 | |||||
| 姓名 | Hashimoto, Shigeo | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In a series of recent studies, extrathymic T cell differentiation in mice has been reported. These T cells may be more primitive than that of thymic origin. Since they carry self reactive forbidden clones, it could be benefical for elimenating their own atypical cells. They express IL-2Rβ similar to NK cells, containing CD4 or CD8 double negative cells. Their morphology is large granular lymphocyte (LGL). This study is to elucidate the possibility that CD56 positive T cells with a morphology of LGL are the counterpart of extrathymic T cells in human. CD56 positive T cells were abundant in the liver comparing in peripheral blood from same donor. The phenotype of T cells in the liver mononuclear cells (MNC), CD56 positive T cells had considerably higher proportion of TCR-γδ aquisition, and CD4, CD8 double negative population were also existed in one of the case who had high population of CD56 positive T cells. While CD56 positive cells were absent in the thymus. CD56 positive T cells were able to proliferate in serum-rich medium condition supplemented with IL-2. CD56 positive T cells were also harvested from bone marrow cells in a liquid culture without thymic environment. These results described above and similarities of the extrathymic T cells in mice, strongly indicate the possibility that CD56 positive T cells is a counterpart of extrathymic T cells in humans. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 108, 号 5, p. 358-366, 発行日 1994-05 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
