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CD4+ helper T cells differentiate functionally into one of two subsets, Th1 or Th2. Th1 cells generate IL-2 and IFN\u03b3 and support the cellular immune responses. On the other hand, Th2 cells generate IL-4, IL-5 and IL-10 and support the humoral immune responses. A unique population of T cells that carry intermediate levels of TCR exist in the liver and other immune organs. These T cells express IL-2R\u03b2-chain and receptors of the NK cell lineage. Many investigators call them intTCR cells or NKT cells. Recently, it was demonstrated that NKT cells produce IL-4 and IFN-\u03b3 and regulate the differentiation of CD4^+ helper T cells into Th1 or Th2 cells. These findings indicate that NKT cells play an important role of immune regulation by cytokines.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "103928", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Watanabe, Hisami"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u6e21\u90e8, \u4e45\u5b9f"}], "nameIdentifiers": [{"nameIdentifier": "103927", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "112(11)_667-670.pdf", "filesize": [{"value": "562.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 562600.0, "url": {"label": "112(11)_667-670.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/16295/files/112(11)_667-670.pdf"}, "version_id": "d43daf4d-6657-4b37-a1bc-4abde525ce20"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "NKT cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cytokines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Th1 and Th2 cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "NKT\u7d30\u80de", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Th1\u3068Th2\u7d30\u80de", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "1)T\u7d30\u80de\u3092\u3081\u3050\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3 : \u6700\u8fd1\u306e\u8a71\u984c\uff08\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u57fa\u790e\u3068\u81e8\u5e8a\u5fdc\u7528, \u7b2c537\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a\uff09", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "1)T\u7d30\u80de\u3092\u3081\u3050\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3 : \u6700\u8fd1\u306e\u8a71\u984c\uff08\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u57fa\u790e\u3068\u81e8\u5e8a\u5fdc\u7528, \u7b2c537\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a\uff09"}, {"subitem_title": "1)T\u7d30\u80de\u3092\u3081\u3050\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3 : \u6700\u8fd1\u306e\u8a71\u984c\uff08\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u57fa\u790e\u3068\u81e8\u5e8a\u5fdc\u7528, \u7b2c537\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a\uff09", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1102"], "permalink_uri": "http://hdl.handle.net/10191/46332", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2017-02-10"}, "publish_date": "2017-02-10", "publish_status": "0", "recid": "16295", "relation": {}, "relation_version_is_last": true, "title": ["1)T\u7d30\u80de\u3092\u3081\u3050\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3 : \u6700\u8fd1\u306e\u8a71\u984c\uff08\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u57fa\u790e\u3068\u81e8\u5e8a\u5fdc\u7528, \u7b2c537\u56de\u65b0\u6f5f\u533b\u5b66\u4f1a\uff09"], "weko_shared_id": null}