{"_buckets": {"deposit": "da64bc21-27e5-43cd-a17f-4deb20e442c7"}, "_deposit": {"id": "12514", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "12514"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00012514", "sets": ["456", "1026"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Effects of Angiotensin II Receptor Blocker in Rats with Daunorubicin-induced Myocardial and Renal Disorders"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2005-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "335", "bibliographicPageStart": "329", "bibliographicVolumeNumber": "119", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "アントラサイクリン系抗悪性腫瘍薬であるダウノルビシン(DNR)は白血病等の治療に多用されているが,時に心臓・腎臓障害を起こすことが知られている.一方,アンジオテンシン受容体拮抗薬(ARB)は主に高血圧患者に用いられているが,最近では腎臓病や心不全患者にも用いられ,その心・腎保護作用が注目されている.そこでDNR心筋障害ラットに対し,ARBのカンデサルタン・シレキセチルを投与し,心臓と腎臓の病理組織像,血行動態について検討した.正常群と比較し,DNR群では心機能の悪化及び腎糸球体・尿細管の障害が見られたが,カンデサルタン投与によりそれらが改善した.以上の結果よりカンデサルタンはDNR心腎障害を改善させると推測された.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", 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