{"_buckets": {"deposit": "fe584a0d-870c-4a1b-a9dc-fe0d85fad5f3"}, "_deposit": {"id": "11557", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "11557"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00011557", "sets": ["456", "1000"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Applications of Advanced Spectroscopy in Medical Pharmacy"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "431", "bibliographicPageStart": "427", "bibliographicVolumeNumber": "121", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "薬物の作用機序を原理的に理解するには,薬物との相互作用に伴う標的生体分子の構造・機能の変化を知る必要がある.このような研究はX線結晶解析や高分解能NMRを用いて行われているが,近年の光発生・検出技術の進歩に伴い,分光学的手法も有力な研究手段となりつつある.中でも共鳴ラマン分光法は,水溶液中で測定が可能であり,固体・溶液にかかわらず測定でき,空間・時間分解能が高く,高選択であるという特徴を持つ.本稿では,ラマン分光法と共鳴ラマン効果について概説した後,共鳴一差ラマン分光による1残基構造変化検出,マイクロ流動チップー顕微ラマン分光による赤血球の脱酸素過程の解析など,ラマン分光法を薬学領域に応用した研究例を紹介する.また,分子分光法は基本的には非破壊計測であり,この特徴を生かしてin situ分析への応用も広がっている.薬剤部業務にin situ分析を応用した例として,テラヘルツ波を用いた薬剤識別装置開発の試みについても述べる.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "78385", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Toyama, Akira"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_relation_31": {"attribute_name": "異版である", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://ci.nii.ac.jp/naid/110007146432", "subitem_relation_type_select": "URI"}}]}, "item_7_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "本文データは学協会の許諾に基づきCiNiiから複製したものである"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "外山, 聡"}], "nameIdentifiers": [{"nameIdentifier": "78384", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "110007146432.pdf", "filesize": [{"value": "603.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 603900.0, "url": {"label": "110007146432.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/11557/files/110007146432.pdf"}, "version_id": "2219d972-fc18-4b88-8cac-9b571a73c046"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ラマン分光法", "subitem_subject_scheme": "Other"}, {"subitem_subject": "テラヘルツ分光", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "最新の分光学的手法の医療薬学領域への応用", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "最新の分光学的手法の医療薬学領域への応用"}, {"subitem_title": "最新の分光学的手法の医療薬学領域への応用", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1000"], "permalink_uri": "http://hdl.handle.net/10191/32760", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-08-04"}, "publish_date": "2015-08-04", "publish_status": "0", "recid": "11557", "relation": {}, "relation_version_is_last": true, "title": ["最新の分光学的手法の医療薬学領域への応用"], "weko_shared_id": null}