{"_buckets": {"deposit": "92881de4-6d07-4b07-a0f5-91c358d7d827"}, "_deposit": {"id": "9354", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9354"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00009354"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Preventive Effect of Irbesartan on Bleomycin-induced Lung Injury in Mice"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "194", "bibliographicPageStart": "185", "bibliographicVolumeNumber": "127", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u306f,\u6162\u6027\u304b\u3064\u9032\u884c\u6027\u306e\u7d4c\u904e\u3092\u3068\u308a,\u9ad8\u5ea6\u306e\u7dda\u7dad\u5316\u3068\u80ba\u80de\u69cb\u7bc9\u306e\u6539\u5909\u304b\u3089\u4e0d\u53ef\u9006\u7684\u306a\u8702\u5de3\u80ba\u5f62\u6210\u306b\u9032\u884c\u3059\u308b\u539f\u56e0\u4e0d\u660e\u306e\u75be\u60a3\u3067\u3042\u308b.\u73fe\u5728\u307e\u3067\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u306f\u78ba\u7acb\u3055\u308c\u3066\u304a\u3089\u305a,\u81ea\u899a\u75c7\u72b6\u51fa\u73fe\u5f8c\u306e\u751f\u5b58\u671f\u9593\u306f\u5e73\u5747\u7d043\u5e74\u3068\u3055\u308c\u308b\u96e3\u6cbb\u6027\u80ba\u75be\u60a3\u3067\u3042\u308b.\u3053\u308c\u307e\u3067\u306e\u5831\u544a\u3067\u306f,\u9593\u8cea\u6027\u80ba\u708e\uff65\u80ba\u7dda\u7dad\u75c7\u3067\u306e\u80ba\u5c40\u6240\u3067\u30ec\u30cb\u30f3\uff65\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u7cfb\u306e\u6d3b\u6027\u5316\u304c\u8d77\u304d\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306b\u3088\u308b\u80ba\u7dda\u7dad\u75c7\u30e2\u30c7\u30eb\u306e\u6539\u5584\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b.\u4e00\u65b9\u3067\u8fd1\u5e74,\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306b\u304a\u3044\u3066,\u53d7\u5bb9\u4f53\u975e\u4f9d\u5b58\u6027\u306e\u65b0\u305f\u306a\u4f5c\u7528\u3092\u5448\u3059\u308b\u30c9\u30e9\u30c3\u30b0\u30a8\u30d5\u30a7\u30af\u30c8\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b.\u30a4\u30eb\u30d9\u30b5\u30eb\u30bf\u30f3\u306b\u304a\u3044\u3066,PPAR_\u03b3\u306e\u90e8\u5206\u6d3b\u6027\u3092\u6709\u3059\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u308b.\u3053\u308c\u307e\u3067\u3082PPAR_\u03b3\u30ea\u30ac\u30f3\u30c9\u306b\u3088\u308b\u80ba\u7dda\u7dad\u75c7\u30e2\u30c7\u30eb\u306e\u6539\u5584\u52b9\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089,\u30ec\u30cb\u30f3\uff65\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u7cfb\u306b\u5bfe\u3059\u308b\u4f5c\u7528\u306b\u52a0\u3048PPAR_\u03b3\u90e8\u5206\u6d3b\u6027\u4f5c\u7528\u3092\u6301\u3064\u30a4\u30eb\u30d9\u30b5\u30eb\u30bf\u30f3\u306e\u80ba\u7dda\u7dad\u5316\u6291\u5236\u52b9\u679c\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u305f.8\u9031\u9f62\u306eICR\u30de\u30a6\u30b9\u306b\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u3092\u6c17\u7ba1\u5185\u306b\u5358\u56de\u6295\u4e0e\u3057,\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u80ba\u7dda\u7dad\u75c7\u30e2\u30c7\u30eb\u3092\u4f5c\u6210\u3057\u305f.\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306fBLM\u6295\u4e0e\u306e5\u65e5\u524d\u304b\u3089\u9023\u65e5,BLM\u6295\u4e0e14\u65e5\u5f8c\u307e\u3067\u80c3\u30be\u30f3\u30c7\u306b\u3088\u308b\u7d4c\u53e3\u6295\u4e0e\u3092\u884c\u3044,GW9662\u306f\u30a4\u30eb\u30d9\u30b5\u30eb\u30bf\u30f3\u6295\u4e0e\u306e1\u6642\u9593\u524d\u306b\u9023\u65e5\u8179\u8154\u5185\u6295\u4e0e\u3057\u305f.14\u65e5\u76ee\u306b,\u6c17\u7ba1\u652f\u80ba\u80de\u6d17\u6d44\uff65\u80ba\u7d44\u7e54\u3092\u542b\u3081\u305f\u30b5\u30f3\u30d7\u30ea\u30f3\u30b0\u3092\u884c\u3063\u305f.\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u6295\u4e0e\u7fa4,\u304a\u3088\u3073\u30a4\u30eb\u30d9\u30b5\u30eb\u30bf\u30f3\u306bPPAR_\u03b3\u30a2\u30f3\u30bf\u30b4\u30cb\u30b9\u30c8\u3067\u3042\u308bGW9662\u3092\u52a0\u3048\u305f\u7fa4\u3092,\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u5358\u72ec\u6295\u4e0e\u7fa4\u3068\u6bd4\u8f03\u3057\u305f.\u30a4\u30eb\u30d9\u30b5\u30eb\u30bf\u30f3\u306e\u524d\u6295\u4e0e\u306b\u3088\u308a,\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u6295\u4e0e\u5f8c14\u65e5\u65e5\u306e\u4f53\u91cd\u6e1b\u5c11,\u80ba\u6e7f\u4e7e\u91cd\u91cf\u5dee\u306e\u5897\u52a0,\u30cf\u30a4\u30c9\u30ed\u30ad\u30b7\u30d7\u30ed\u30ea\u30f3\u91cf\u306e\u5897\u52a0,\u80ba\u7d44\u7e54\u6240\u898b\u306b\u304a\u3051\u308b\u80ba\u7dda\u7dad\u5316\u30b9\u30b3\u30a2\u304c\u5168\u3066\u6709\u610f\u306b\u6291\u5236\u3055\u308c\u305f.\u307e\u305fBALF\u4e2d\u306e\u7dcf\u7d30\u80de\u6570,\u30de\u30af\u30ed\u30d5\u30a1-\u30b8\u6570\u306e\u5897\u52a0,TGF-\u03b21,MCP-1\u6fc3\u5ea6\u306e\u4e0a\u6607\u304c\u6709\u610f\u306b\u6291\u5236\u3055\u308c\u305f.PPAR_\u03b3\u30a2\u30f3\u30bf\u30b4\u30cb\u30b9\u30c8GW9662\u306f,\u4e0a\u8a18\u306e\u7d50\u679c\u306b\u5bfe\u3057\u3066\u90e8\u5206\u7684\u306b\u6291\u5236\u52b9\u679c\u306e\u6e1b\u5f31\u3092\u793a\u3057\u305f.\u4ee5\u4e0a\u3088\u308a,\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306f\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u6295\u4e0e\u85ac\u3068\u3057\u3066\u306e\u4f5c\u7528\u3060\u3051\u3067\u306a\u304f,PPAR_\u03b3\u6d3b\u6027\u5316\u4f5c\u7528\u3092\u4ecb\u3057\u3066,\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u306b\u3088\u308b\u80ba\u7dda\u7dad\u5316\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u305f.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "64945", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Tanaka, Jun-ichi"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u7530\u4e2d, \u6df3\u4e00"}], "nameIdentifiers": [{"nameIdentifier": "64944", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "127(4)_185-194.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "127(4)_185-194.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/9354/files/127(4)_185-194.pdf"}, "version_id": "89d46426-bbd9-4d78-a3b1-eec058d4b32d"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "\u80ba\u7dda\u7dad\u75c7", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PPAR_\u03b3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MCP-1", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u80ba\u7dda\u7dad\u75c7\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306e\u6709\u52b9\u6027\u306e\u691c\u8a0e", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u80ba\u7dda\u7dad\u75c7\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306e\u6709\u52b9\u6027\u306e\u691c\u8a0e"}, {"subitem_title": "\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u80ba\u7dda\u7dad\u75c7\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306e\u6709\u52b9\u6027\u306e\u691c\u8a0e", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/932"], "permalink_uri": "http://hdl.handle.net/10191/35840", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-12-22"}, "publish_date": "2015-12-22", "publish_status": "0", "recid": "9354", "relation": {}, "relation_version_is_last": true, "title": ["\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u80ba\u7dda\u7dad\u75c7\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30a4\u30eb\u3079\u30b5\u30eb\u30bf\u30f3\u306e\u6709\u52b9\u6027\u306e\u691c\u8a0e"], "weko_shared_id": null}