{"_buckets": {"deposit": "282d73fe-943a-46b9-8417-29e49c176270"}, "_deposit": {"id": "9316", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9316"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00009316", "sets": ["456", "931"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Histopathologic Features of Epileptogenic Brain Lesions"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "227", "bibliographicPageStart": "221", "bibliographicVolumeNumber": "127", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "難治性てんかん患者に対する外科手術が広く行われるようになり, その摘出脳組織に対する病理学的理解が進んできた. そこには, 発生異常, 神経細胞脱落, 腫瘍性病変, 血管異常, 炎症性病変, 組織破壊性病変など, 多彩なetiologyを示唆する所見が認められる. 小児期あるいはそれ以前に発症する症例では, その病態形成に脳の発生異常が深く関与している場合も多い. その代表的病態のひとつである限局性皮質異形成(FCD:focal cortical dysplasia)では, 皮質神経細胞の配列がさまざまな程度に乱れている. 高度の乱れを示す場合には, dysmorphic neuronやballoon cellと呼ばれる異型細胞を伴っている. こうした症例はFCD Type IIと分類されている. 一方, 異型細胞を伴わない場合はFCD Type Iと分類されている. この場合には, 通常, 神経細胞の配列の乱れは軽い． 結節性硬化症の皮質結節や片側巨脳症でも, FCD Type IIの異型細胞に類似した細胞が出現する. てんかん原性病巣の病態理解に向け, 神経生理学や発生学, 更には分子生物学的手法を取り入れた統合的解析が行われている. 神経病理学が果たす役割も大きい.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "64736", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kakita, Akiyoshi"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "柿田, 明美"}], "nameIdentifiers": [{"nameIdentifier": "64735", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "127(5)_221-227.pdf", "filesize": [{"value": "2.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2600000.0, "url": {"label": "127(5)_221-227.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/9316/files/127(5)_221-227.pdf"}, "version_id": "43154018-2bca-446f-a329-138eb0a3cda2"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "皮質異形成", "subitem_subject_scheme": "Other"}, {"subitem_subject": "発生異常", "subitem_subject_scheme": "Other"}, {"subitem_subject": "てんかん", "subitem_subject_scheme": "Other"}, {"subitem_subject": "神経細胞移動", "subitem_subject_scheme": "Other"}, {"subitem_subject": "病理", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "てんかん外科病理学の実際", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "てんかん外科病理学の実際"}, {"subitem_title": "てんかん外科病理学の実際", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "931"], "permalink_uri": "http://hdl.handle.net/10191/35972", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-12-22"}, "publish_date": "2015-12-22", "publish_status": "0", "recid": "9316", "relation": {}, "relation_version_is_last": true, "title": ["てんかん外科病理学の実際"], "weko_shared_id": null}