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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第127巻第7号

3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会)

http://hdl.handle.net/10191/36051
http://hdl.handle.net/10191/36051
b3adfb49-f784-47eb-9b5f-ed0821148c7c
名前 / ファイル ライセンス アクション
127(7)_349-354.pdf 127(7)_349-354.pdf (477.1 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-12-25
タイトル
タイトル 3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会)
タイトル
言語 en
タイトル 3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 chronic periodontitis
キーワード
主題Scheme Other
主題 cultured periosteal sheet
キーワード
主題Scheme Other
主題 clinical attachment level
キーワード
主題Scheme Other
主題 radiographic infrabony defect depth
キーワード
主題Scheme Other
主題 Wilcoxon signed-rank test
キーワード
主題Scheme Other
主題 Mann-Whitney U test
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Tissue Engineered Cultured Periosteal Sheet Application to Periodontal Regeneration : How to Collect and Evaluate Data(The Strategy to Activate Clinical Research in Niigata University)
著者 奥田, 一博

× 奥田, 一博

WEKO 64375

奥田, 一博

Search repository
吉江, 弘正

× 吉江, 弘正

WEKO 64376

吉江, 弘正

Search repository
川瀬, 知之

× 川瀬, 知之

WEKO 64377

川瀬, 知之

Search repository
中田, 光

× 中田, 光

WEKO 64378

中田, 光

Search repository
著者別名
識別子 64379
識別子Scheme WEKO
姓名 Okuda, Kazuhiro
著者別名
識別子 64380
識別子Scheme WEKO
姓名 Yoshie, Hiromasa
著者別名
識別子 64381
識別子Scheme WEKO
姓名 Kawase, Tomoyuki
著者別名
識別子 64382
識別子Scheme WEKO
姓名 Nakata, Koh
抄録
内容記述タイプ Abstract
内容記述 To regenerate periodontal tissue destroyed by chronic periodontitis, autologous cultured periosteal sheets in combination with platelet-rich plasma (PRP) and hydroxyapatite (HA) granules were used as a clinical application. The periosteum specimens were dissected from each patient, and were incubated for approximately six weeks until the sheets were formed. Prior to placement of the cultured periosteal sheets, osseous defects were thoroughly debrided and filled with HA granules in combination with PRP. Standardized clinical and radiographic measurements were determined during follow-up examinations at one, two and three years. Clinical attachment level (CAL) and radiographic infrabony defect depth (IBD) were determined as primary end-point. As secondary end-point, inflammatory indices including plaque index (PI), gingival index (GI) and bleeding on probing (BOP) were determined. Results were averaged for the clinical and radiographic parameters. Taking into account the paired nature of the changes from baseline to one year, and three years in each group, the Wilcoxon signed-rank test was performed. The Mann-Whitney U test was applied to compare clinical and radiographic outcomes between test and control groups at baseline and 1 year post surgery. The null hypothesis was rejected when the risk percentage was < 5% (p<0.05). One year results of this treatment have shown favorable clinical results, and these effects were stable and maintained after three years, when compared to baseline. The cultured periosteal sheets function as a living drug delivery system to favorably influence cellular functions and serves as seeds for ectopic bone formation near the implantation site through production of important growth factors related to periodontal regeneration.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 127, 号 7, p. 349-354, 発行日 2013-07
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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