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3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会)
http://hdl.handle.net/10191/36051
http://hdl.handle.net/10191/36051b3adfb49-f784-47eb-9b5f-ed0821148c7c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
127(7)_349-354.pdf (477.1 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-12-25 | |||||
| タイトル | ||||||
| タイトル | 3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会) | |||||
| タイトル | ||||||
| タイトル | 3 自己培養骨膜シートを用いた歯槽骨再生研究 : データをどのように収集してどのように評価するか(シンポジウム 新潟大学の臨床研究を活性化するためにはどのような仕組みが必要か?, 第672回新潟医学会) | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | chronic periodontitis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cultured periosteal sheet | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | clinical attachment level | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | radiographic infrabony defect depth | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Wilcoxon signed-rank test | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Mann-Whitney U test | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Tissue Engineered Cultured Periosteal Sheet Application to Periodontal Regeneration : How to Collect and Evaluate Data(The Strategy to Activate Clinical Research in Niigata University) | |||||
| 著者 |
奥田, 一博
× 奥田, 一博× 吉江, 弘正× 川瀬, 知之× 中田, 光 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 64379 | |||||
| 姓名 | Okuda, Kazuhiro | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 64380 | |||||
| 姓名 | Yoshie, Hiromasa | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 64381 | |||||
| 姓名 | Kawase, Tomoyuki | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 64382 | |||||
| 姓名 | Nakata, Koh | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To regenerate periodontal tissue destroyed by chronic periodontitis, autologous cultured periosteal sheets in combination with platelet-rich plasma (PRP) and hydroxyapatite (HA) granules were used as a clinical application. The periosteum specimens were dissected from each patient, and were incubated for approximately six weeks until the sheets were formed. Prior to placement of the cultured periosteal sheets, osseous defects were thoroughly debrided and filled with HA granules in combination with PRP. Standardized clinical and radiographic measurements were determined during follow-up examinations at one, two and three years. Clinical attachment level (CAL) and radiographic infrabony defect depth (IBD) were determined as primary end-point. As secondary end-point, inflammatory indices including plaque index (PI), gingival index (GI) and bleeding on probing (BOP) were determined. Results were averaged for the clinical and radiographic parameters. Taking into account the paired nature of the changes from baseline to one year, and three years in each group, the Wilcoxon signed-rank test was performed. The Mann-Whitney U test was applied to compare clinical and radiographic outcomes between test and control groups at baseline and 1 year post surgery. The null hypothesis was rejected when the risk percentage was < 5% (p<0.05). One year results of this treatment have shown favorable clinical results, and these effects were stable and maintained after three years, when compared to baseline. The cultured periosteal sheets function as a living drug delivery system to favorably influence cellular functions and serves as seeds for ectopic bone formation near the implantation site through production of important growth factors related to periodontal regeneration. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 127, 号 7, p. 349-354, 発行日 2013-07 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
