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Immunohistochemical investigation of cartilaginous tumors
http://hdl.handle.net/10191/33573
http://hdl.handle.net/10191/3357337540f8a-c10c-4058-a4bf-f51828ef1c7c
名前 / ファイル | ライセンス | アクション |
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35(1)_35-44.pdf (2.0 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-10-07 | |||||
タイトル | ||||||
タイトル | Immunohistochemical investigation of cartilaginous tumors | |||||
タイトル | ||||||
タイトル | Immunohistochemical investigation of cartilaginous tumors | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Chondrosarcoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | S-100 protein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alpha-1-antitrypsin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alpha-1-antichymotrypsin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cartilaginous tumor | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Inoue, Yoshiya
× Inoue, Yoshiya |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Twenty-eight cartilaginous tumors and normal bronchial cartilages were investigated immunohistochemically by using the antibodies to S-100 protein, alpha-1-antitrypsin (AT) and alpha-1-antichymotrypsin (ACT). All lesions and normal control specimens were revealed to have S-100 protein positive chondrocytes in various frequencies. The staining pattern of chondrocytes could be divided into three different types: D (diffusely stained) type, C (cytoplasmic dominant) type and N (nuclear dominant) type. All cartilaginous lesions except two immature teratomas had AT positive chondrocytes and these cells were found much more in malignant tumors than in benign ones. ACT positive chondrocytes were observed in two osteosarcomas, in all chondrosarcomas, and in one of two borderline cartilaginous tumors but no positive cells were seen in benign lesions. From these findings, the appearance of AT positive chondrocytes strongly indicates that the lesions were truely neoplastic. Furthermore the existence of ACT positive chondrocytes in tumors was considered to be a useful marker of malignancy. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 35, 号 1, p. 35-44, 発行日 1987-06 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |