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Induction of Cytotoxic T Lymphocytes against Allogeneic Leukemia Cell Line
http://hdl.handle.net/10191/33441
http://hdl.handle.net/10191/3344163bd6682-aa35-4a8e-91ed-5c3daab40852
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-28 | |||||
タイトル | ||||||
タイトル | Induction of Cytotoxic T Lymphocytes against Allogeneic Leukemia Cell Line | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Induction of Cytotoxic T Lymphocytes against Allogeneic Leukemia Cell Line | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Maruyama, Soichi
× Maruyama, Soichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In order to apply specific cytotoxic T lymphocytes (CTL) to human leukemia therapy, the induction of CTL against an allogeneic leukemia cell line from healthy volunteers and leukemia patients in remission was performed. Cytotoxicity was measured after mixed lymphocytetumor cell culture (MLTC) of peripheral blood lymphocytes (PBL) from healthy volunteers or patients and mitomycin C (MMC) treated YS-1 which is an alloleukemia cell line. The results were as follows: 1) CTL were induced from PBL of both healthy volunteers and leukemia patients in remission; 2) in leukemia patients, CTL activity varied according to disease conditions; 3) a secondary culture induced significantly higher CTL activity than a primary culture. These results suggest the feasibility of adoptive immunotherapy (AIT) for human leukemias using specific CTL. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 39, 号 2, p. 83-90, 発行日 1991-06 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |