{"_buckets": {"deposit": "2b984755-30e6-4ffc-ad5b-a383b30104b1"}, "_deposit": {"id": "6600", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6600"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006600"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "81", "bibliographicPageStart": "75", "bibliographicVolumeNumber": "39", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A new cultured cell line (ACL-15) was established from a transplantable rat colon cancer strain induced by 1, 2-dimethyl hydrazine (DMH). Histologically, the primary colonic tumor was a poorly differentiated adenocarcinoma; all transplanted tumors showed the same histologic features. The doubling time of the ACL-15 cell line population was 24 h, and the saturation density was 5.6 x 10^5 cells/cm^2 in culture. The chromosome number and DNA content of the ACL-15 cells were near tetraploid. ACL-15 cells frequently metastasized to the liver and lungs in vivo. Thirty percent of those rats inoculated with ACL-15 cells into the subserosa of the cecum and all rats which received intrasplenic inoculations of ACL-15 cells developed hepatic metastases. All rats injected with ACL-15 into subcutis and into the tail vein developed multiple pulmonary metastases. This newly established cell line, ACL15, can serve for a model of metastatic colonic cancer.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kashima, Yuji"}], "nameIdentifiers": [{"nameIdentifier": "53627", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "39(2)_75-81.pdf", "filesize": [{"value": "2.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2500000.0, "url": {"label": "39(2)_75-81.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6600/files/39(2)_75-81.pdf"}, "version_id": "6b904e7d-dee3-4919-90f7-28267c9d0737"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties"}, {"subitem_title": "The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/641"], "permalink_uri": "http://hdl.handle.net/10191/33440", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-09-28"}, "publish_date": "2015-09-28", "publish_status": "0", "recid": "6600", "relation": {}, "relation_version_is_last": true, "title": ["The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties"], "weko_shared_id": null}