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The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties
http://hdl.handle.net/10191/33440
http://hdl.handle.net/10191/334407840d0e4-06a8-46d0-ad22-9bfd8cdcb31d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
39(2)_75-81.pdf (2.5 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-09-28 | |||||
| タイトル | ||||||
| タイトル | The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties | |||||
| タイトル | ||||||
| タイトル | The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Kashima, Yuji
× Kashima, Yuji |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A new cultured cell line (ACL-15) was established from a transplantable rat colon cancer strain induced by 1, 2-dimethyl hydrazine (DMH). Histologically, the primary colonic tumor was a poorly differentiated adenocarcinoma; all transplanted tumors showed the same histologic features. The doubling time of the ACL-15 cell line population was 24 h, and the saturation density was 5.6 x 10^5 cells/cm^2 in culture. The chromosome number and DNA content of the ACL-15 cells were near tetraploid. ACL-15 cells frequently metastasized to the liver and lungs in vivo. Thirty percent of those rats inoculated with ACL-15 cells into the subserosa of the cecum and all rats which received intrasplenic inoculations of ACL-15 cells developed hepatic metastases. All rats injected with ACL-15 into subcutis and into the tail vein developed multiple pulmonary metastases. This newly established cell line, ACL15, can serve for a model of metastatic colonic cancer. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 39, 号 2, p. 75-81, 発行日 1991-06 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Kashima, Yuji, 1991, The Establishment of a Rat Colon Cancer Cell Line, ACL-15, with an Analysis of Its Metastatic Properties: Niigata University School of Medicine, 75–81 p.
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