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Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice
http://hdl.handle.net/10191/33450
http://hdl.handle.net/10191/3345034f0bc2c-b986-463a-a81e-bf7f62ce829c
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-28 | |||||
タイトル | ||||||
タイトル | Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Kaga, Hidetoshi
× Kaga, Hidetoshi× Ochiai, Hiroshi× Kurokawa, Masahiko× Sakuragawa, Nobuo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We have investigated the effects of Kampohozais (Traditional herbal drugs: Sho-saiko-to 小柴胡湯, Ninjin-to 人参湯, Hochu-ekki-to 補中益気湯,and Juzentaiho-to 十全大補湯) on immune responses in mice. Ninjin-to augmented the natural killer (NK) cell activity by a single intraperitoneal administration at doses of either 50, 100 or 200 mg/kg. Sho-saiko-to also augmented this activity at a dose of 100 mg/kg, but suppressed it at a dose of 200 mg/kg. An oral administration of Sho-saiko-to and Ninjin-to once a day at a dose of 250 mg/kg augmented the NK cell activity 7 and 20 days later, respectively. The effect of the remaining two Kampohozais was negligible. Four Kampohozais each exhibited a stronger mitogenic activity on B cell-rich population than on T cell-rich population, suggesting that these Kampohozais act as B cell mitogens. Treatment of mice with Sho-saiko-to by oral administration once a day for 13 days at a dose of 250 mg/kg increased the number of splenic antibody-producing cells against sheep erythrocytes, accompanied with an increase in both serum hemagglutinin and hemolysin titers. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 39, 号 4, p. 161-167, 発行日 1991-12 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |