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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.39 No.4

Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice

http://hdl.handle.net/10191/33450
http://hdl.handle.net/10191/33450
34f0bc2c-b986-463a-a81e-bf7f62ce829c
名前 / ファイル ライセンス アクション
39(4)_161-167.pdf 39(4)_161-167.pdf (823.1 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-09-28
タイトル
タイトル Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice
タイトル
言語 en
タイトル Effects of Kampohozais (Sho-saiko-to, Ninjin-to, Hochu-ekki-to and Juzen-taiho-to) on Immune Responses in Mice
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Kaga, Hidetoshi

× Kaga, Hidetoshi

WEKO 53591

Kaga, Hidetoshi

Search repository
Ochiai, Hiroshi

× Ochiai, Hiroshi

WEKO 53592

Ochiai, Hiroshi

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Kurokawa, Masahiko

× Kurokawa, Masahiko

WEKO 53593

Kurokawa, Masahiko

Search repository
Sakuragawa, Nobuo

× Sakuragawa, Nobuo

WEKO 53594

Sakuragawa, Nobuo

Search repository
抄録
内容記述タイプ Abstract
内容記述 We have investigated the effects of Kampohozais (Traditional herbal drugs: Sho-saiko-to 小柴胡湯, Ninjin-to 人参湯, Hochu-ekki-to 補中益気湯,and Juzentaiho-to 十全大補湯) on immune responses in mice. Ninjin-to augmented the natural killer (NK) cell activity by a single intraperitoneal administration at doses of either 50, 100 or 200 mg/kg. Sho-saiko-to also augmented this activity at a dose of 100 mg/kg, but suppressed it at a dose of 200 mg/kg. An oral administration of Sho-saiko-to and Ninjin-to once a day at a dose of 250 mg/kg augmented the NK cell activity 7 and 20 days later, respectively. The effect of the remaining two Kampohozais was negligible. Four Kampohozais each exhibited a stronger mitogenic activity on B cell-rich population than on T cell-rich population, suggesting that these Kampohozais act as B cell mitogens. Treatment of mice with Sho-saiko-to by oral administration once a day for 13 days at a dose of 250 mg/kg increased the number of splenic antibody-producing cells against sheep erythrocytes, accompanied with an increase in both serum hemagglutinin and hemolysin titers.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 39, 号 4, p. 161-167, 発行日 1991-12
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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