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Immunologic States Induced by Starvation : Suppression of Intrathymic T-cell Differentiation Contrasting with the Relative Resistance of Extrathymic T-cell Differentiation
http://hdl.handle.net/10191/33331
http://hdl.handle.net/10191/33331a5500c7c-4e03-4f41-bd68-bc248e8016a1
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-11 | |||||
タイトル | ||||||
タイトル | Immunologic States Induced by Starvation : Suppression of Intrathymic T-cell Differentiation Contrasting with the Relative Resistance of Extrathymic T-cell Differentiation | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Immunologic States Induced by Starvation : Suppression of Intrathymic T-cell Differentiation Contrasting with the Relative Resistance of Extrathymic T-cell Differentiation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Ogawa, Mitsuru
× Ogawa, Mitsuru× Iiai, Tsuneo× Hirahara, Hiroyuki× Tomiyama, Katsuhiro× Kawachi, Yasuyuki× Watanabe, Hisami× Shimoji, Koki× Abo, Toru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Immunologic states induced by starvation were investigated in mice. Attention was focused on not only T cells of thymic origin but also extrathymically differentiated T cells. It was demonstrated that the numbers of lymphocytes yielded by the various immune organs, including the liver, spleen and thymus, prominently decreased during starvation (4-day period). At this time, intrathymic T-cell differentiation was profoundly suppressed and the number of thymus-derived T cells in the peripheral organs decreased. On the other hand, extrathymic T cells did not significantly decrease in number, especially in the liver. During starvation, a stress-associated glucocorticoid, corticosterone, was elevated in the serum of these mice. Since the in vivo injection of hydrocortisone induced a response similar to that seen during starvation, it is likely that glucocorticoids as well as a cessation of energy supply participates in immunologic states induced by starvation. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 41, 号 4, p. 177-187, 発行日 1993-12 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |