@article{oai:niigata-u.repo.nii.ac.jp:00006515,
 author = {Ogawa, Mitsuru and Iiai, Tsuneo and Hirahara, Hiroyuki and Tomiyama, Katsuhiro and Kawachi, Yasuyuki and Watanabe, Hisami and Shimoji, Koki and Abo, Toru},
 issue = {4},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Dec},
 note = {Immunologic states induced by starvation were investigated in mice. Attention was focused on not only T cells of thymic origin but also extrathymically differentiated T cells. It was demonstrated that the numbers of lymphocytes yielded by the various immune organs, including the liver, spleen and thymus, prominently decreased during starvation (4-day period). At this time, intrathymic T-cell differentiation was profoundly suppressed and the number of thymus-derived T cells in the peripheral organs decreased. On the other hand, extrathymic T cells did not significantly decrease in number, especially in the liver. During starvation, a stress-associated glucocorticoid, corticosterone, was elevated in the serum of these mice. Since the in vivo injection of hydrocortisone induced a response similar to that seen during starvation, it is likely that glucocorticoids as well as a cessation of energy supply participates in immunologic states induced by starvation.},
 pages = {177--187},
 title = {Immunologic States Induced by Starvation : Suppression of Intrathymic T-cell Differentiation Contrasting with the Relative Resistance of Extrathymic T-cell Differentiation},
 volume = {41},
 year = {1993}
}