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Argentaffin Carcinoid Tumors of the Rectum : An Immunohistochemical and Ultrastructural Study
http://hdl.handle.net/10191/33244
http://hdl.handle.net/10191/332445ad51e7b-e401-4470-9bad-08cb794b298c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
42(2)_79-86.pdf (1.3 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-09-04 | |||||
| タイトル | ||||||
| タイトル | Argentaffin Carcinoid Tumors of the Rectum : An Immunohistochemical and Ultrastructural Study | |||||
| タイトル | ||||||
| タイトル | Argentaffin Carcinoid Tumors of the Rectum : An Immunohistochemical and Ultrastructural Study | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Iwafuchi, Mitsuya
× Iwafuchi, Mitsuya× Watanabe, Hidenobu× Nishikura, Ken× Tanaka, Kazuo× Noda, Yutaka× Itagaki, Tetsurou |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Nine argentaffin carcinoids were found among 94 rectal classical carcinoids (9.6% in frequency), and were systematically investigated regarding histologic, immunohistochemical and ultrastructural characteristics, in addition to the prognosis of patients. The carcinoids were characterized by a trabecular pattern frequently exhibiting an acinar arrangement of tumor cells with intracytoplasmic red-brown granules on routine hematoxylin-eosin (HE) staining. Their incidences of hormone-immunoreactivities were as follows: serotonin, 100%; neurotensin, 33%; somatostatin, 29%; glicentin, 20%; peptide YY, 20%; and pancreatic polypeptide, 14%. Ultrastructurally, the tumors were composed mainly of ECl and/or ECn cells. Among them, one tumor showed atypical nuclei, a few mitoses, and regional lymph nodal metastasis at the time of primary tumor resection. However, others revealed uniform nuclei, but neither mitosis nor nodal metastasis. Goblet cell differentiation was not found in any of the carcinoids. No patients had any recurrence or metastasis in the course of 1.5 to 7.5 years of follow-up. We conclude that rectal argentaffin carcinoids should be categorized as a distinct group, and that they behave in a low-grade malignant manner except for cases with higher nuclear atypia and mitotic activity. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 42, 号 2, p. 79-86, 発行日 1994-06 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Iwafuchi, Mitsuya, Watanabe, Hidenobu, Nishikura, Ken, Tanaka, Kazuo, Noda, Yutaka, Itagaki, Tetsurou, 1994, Argentaffin Carcinoid Tumors of the Rectum : An Immunohistochemical and Ultrastructural Study: Niigata University School of Medicine, 79–86 p.
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