{"_buckets": {"deposit": "8d5c96d0-fd27-4c98-a1b5-4b52caff3e31"}, "_deposit": {"id": "6426", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6426"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006426"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1996-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "140", "bibliographicPageStart": "135", "bibliographicVolumeNumber": "44", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "We investigated the macrophage inflammatory protein-2 (MIP-2)-producing activity of respiratory syncytial virus (RSV) in a murine macrophage cell line, RAW 264.7 cells, and airway-lining cells by the application of recently developed enzyme-linked immunosorbent assay (ELISA) system. The production of MIP-2 increased significantly in both cells by the infections of RSV in a dose-dependent manner. In addition to ELISA, MIP-2 production could be detected in RSV-infected airway-lining cells by immunocytochemical study. The heat-inactivated virus also enhanced MIP-2 production to comparable levels of the infections with the active virus. Time-related production showed a trend for a biphasic pattern, suggesting that this phenomenon might be due to the combined effects of the direct MIP-2-inducing activity of RSV and an indirect one via the initial production of other cytokines inducible for MIP-2 production. These data indicate that RSV, either in active or inactive form, has the potential to stimulate MIP-2 production in a cultured macrophage cell line and airway-lining cells.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ochiai, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "52857", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Shinya"}], "nameIdentifiers": [{"nameIdentifier": "52858", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakajima, Katsuhisa"}], "nameIdentifiers": [{"nameIdentifier": "52859", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "52860", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Terasawa, Katsutoshi"}], "nameIdentifiers": [{"nameIdentifier": "52861", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "44(3)_135-140.pdf", "filesize": [{"value": "867.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 867900.0, "url": {"label": "44(3)_135-140.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6426/files/44(3)_135-140.pdf"}, "version_id": "614db38d-f49c-4eb3-ad02-809592c28f67"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "respiratory syncytial virus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "macrophage inflammatory protein-2", "subitem_subject_scheme": "Other"}, {"subitem_subject": "interleukin-8", "subitem_subject_scheme": "Other"}, {"subitem_subject": "macrophages", "subitem_subject_scheme": "Other"}, {"subitem_subject": "airway-lining cells", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells"}, {"subitem_title": "Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/618"], "permalink_uri": "http://hdl.handle.net/10191/33171", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-08-27"}, "publish_date": "2015-08-27", "publish_status": "0", "recid": "6426", "relation": {}, "relation_version_is_last": true, "title": ["Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells"], "weko_shared_id": null}