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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.44 No.3

Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells

http://hdl.handle.net/10191/33171
http://hdl.handle.net/10191/33171
0fc55172-e747-4383-9981-20e9fcbc3eeb
名前 / ファイル ライセンス アクション
44(3)_135-140.pdf 44(3)_135-140.pdf (867.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-08-27
タイトル
タイトル Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells
タイトル
言語 en
タイトル Inducing Activity of Respiratory Syncytial Virus on the Production of Macrophage Inflammatory Protein-2 in Murine Macrophages and Airway-lining Cells
言語
言語 eng
キーワード
主題Scheme Other
主題 respiratory syncytial virus
キーワード
主題Scheme Other
主題 macrophage inflammatory protein-2
キーワード
主題Scheme Other
主題 interleukin-8
キーワード
主題Scheme Other
主題 macrophages
キーワード
主題Scheme Other
主題 airway-lining cells
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Ochiai, Hiroshi

× Ochiai, Hiroshi

WEKO 52857

Ochiai, Hiroshi

Search repository
Sakai, Shinya

× Sakai, Shinya

WEKO 52858

Sakai, Shinya

Search repository
Nakajima, Katsuhisa

× Nakajima, Katsuhisa

WEKO 52859

Nakajima, Katsuhisa

Search repository
Sakai, Takeshi

× Sakai, Takeshi

WEKO 52860

Sakai, Takeshi

Search repository
Terasawa, Katsutoshi

× Terasawa, Katsutoshi

WEKO 52861

Terasawa, Katsutoshi

Search repository
抄録
内容記述タイプ Abstract
内容記述 We investigated the macrophage inflammatory protein-2 (MIP-2)-producing activity of respiratory syncytial virus (RSV) in a murine macrophage cell line, RAW 264.7 cells, and airway-lining cells by the application of recently developed enzyme-linked immunosorbent assay (ELISA) system. The production of MIP-2 increased significantly in both cells by the infections of RSV in a dose-dependent manner. In addition to ELISA, MIP-2 production could be detected in RSV-infected airway-lining cells by immunocytochemical study. The heat-inactivated virus also enhanced MIP-2 production to comparable levels of the infections with the active virus. Time-related production showed a trend for a biphasic pattern, suggesting that this phenomenon might be due to the combined effects of the direct MIP-2-inducing activity of RSV and an indirect one via the initial production of other cytokines inducible for MIP-2 production. These data indicate that RSV, either in active or inactive form, has the potential to stimulate MIP-2 production in a cultured macrophage cell line and airway-lining cells.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 44, 号 3, p. 135-140, 発行日 1996-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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