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Effects of Dietary Factors (Fat and Fiber) on Experimental Colon Carcinogenesis and Cancer Growth in Rats
http://hdl.handle.net/10191/33122
http://hdl.handle.net/10191/33122a152cb25-2265-4d5a-98bc-a9ea9656db43
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
45(2)_69-73.pdf (668.7 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-08-25 | |||||
| タイトル | ||||||
| タイトル | Effects of Dietary Factors (Fat and Fiber) on Experimental Colon Carcinogenesis and Cancer Growth in Rats | |||||
| タイトル | ||||||
| タイトル | Effects of Dietary Factors (Fat and Fiber) on Experimental Colon Carcinogenesis and Cancer Growth in Rats | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 1,2-dimethylhydrazine (DMH) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | experimental colon cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | dietary factors | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | fat | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | fiber | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Endo, Kazuhiko
× Endo, Kazuhiko× Hatakeyama, Katsuyoshi× Soga, Jun× Muto, Terukazu |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The effects of dietary fat and fiber on colonic carcinogenesis and tumor growth in rats were assessed. Over a period of 30 weeks, four groups of 10 animals were fed diets with: high fat and high fiber content; high fat content and no fiber; no fat and high fiber content; or no fat and no fiber. Five weeks after starting these diets, each group was divided into two subgroups, one receiving 10 weekly injections of the carcinogen 1, 2-dimethylhydrazine (DMH); (20 mg/kg/ week). The other (control) subgroups recieved no DMH. At 30 weeks the rats were killed and autopsies were performed. Results showed cancers were limited to rats receiving DMH. The average numbers of cancers per rat were 4.8±2.6 for the high fat and fiber group; 6.2± 4.6 for the high fat, no fiber group; 2.3± 1.5 for no fat, high fiber; and 2.2±0.8 for no fat, no fiber. High-fat animals tended to have more DMH-induced cancers than no-fat animals. Aggregate cancer volume per rat was smallest for the no-fat, high-fiber diet. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 45, 号 2, p. 69-73, 発行日 1997-06 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
