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Orally Administered Ginseng Extract Stimulates Liver Regeneration in Partially Hepatectomized Rats
http://hdl.handle.net/10191/33136
http://hdl.handle.net/10191/3313655ffab6d-9d8f-4cec-a208-a377b4afbd55
名前 / ファイル | ライセンス | アクション |
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45(4)_161-166.pdf (1.7 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-08-25 | |||||
タイトル | ||||||
タイトル | Orally Administered Ginseng Extract Stimulates Liver Regeneration in Partially Hepatectomized Rats | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Orally Administered Ginseng Extract Stimulates Liver Regeneration in Partially Hepatectomized Rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | saponin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver resection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatocyte proliferation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rat | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Cui, Xing
× Cui, Xing |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The effects of the oral administration of ginseng extract (GE, the root of panax ginseng C. A. Meyer) and its constituents (GRG, ginsenoside-Rg_1 and GRB, ginsenoside-Rbl_1) on liver regeneration were examined in 66% hepatectmized rats. When liver regeneration was evaluated by the mitotic index of the hepatocyte (MI), a significant increase in the MI was observed 2 and 3 days after GE administration, and the MI response was dose-dependent. Food intake was not affected by GE administration, nor there was any change in the serum insulin concentration. It was also noted that the oral administration of GRG produced a MI response similar to that caused by GE administration. Serum parameters indicating liver and kidney function were unchanged after GE administration. These observations lead us to conclude that orally administered GE and its specific constituent are capable of stimulating liver regeneration without serious systemic effects. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 45, 号 4, p. 161-166, 発行日 1997-12 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |