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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.46 No.3

Prevalence of Male Sex among Families with Sickle Cell Anemia

http://hdl.handle.net/10191/33088
http://hdl.handle.net/10191/33088
167b8832-5685-4b8f-bd9f-fbcb07c69229
名前 / ファイル ライセンス アクション
46(3)_109-111.pdf 46(3)_109-111.pdf (400.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-08-21
タイトル
タイトル Prevalence of Male Sex among Families with Sickle Cell Anemia
タイトル
言語 en
タイトル Prevalence of Male Sex among Families with Sickle Cell Anemia
言語
言語 eng
キーワード
主題Scheme Other
主題 sex ratio
キーワード
主題Scheme Other
主題 sickle cell anemia
キーワード
主題Scheme Other
主題 fetal hemoglobin
キーワード
主題Scheme Other
主題 acute hemolytic episodes
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Khaja, M. N.

× Khaja, M. N.

WEKO 52601

Khaja, M. N.

Search repository
Vishnupriya, S.

× Vishnupriya, S.

WEKO 52602

Vishnupriya, S.

Search repository
Veerraju, P.

× Veerraju, P.

WEKO 52603

Veerraju, P.

Search repository
Habeebullah, C. M.

× Habeebullah, C. M.

WEKO 52604

Habeebullah, C. M.

Search repository
抄録
内容記述タイプ Abstract
内容記述 In the present study the frequency of hemoglobin'S' was determined based on 10 tribal families and 31 non-tribal families of Andhra Pradesh, South India. The incidence of sickle cell anemia was found to be high in males as compared to females in both populations. Sickle cell trait remained more or less equal in both sexes. The gene frequency (q) of HbS was also predominantly high in males (0.231, 0.387 and 0.347) as compared with females (0.072, 0.297 and 0.241) in native, nonnative, and pooled sample' respectively. Sex ratio in HbSS individuals in both groups was found to be 2: 1, which showed a statistical significance, whereas no such deviation was observed in heterozygotes (SS). There was no significant relationship between parental genotypes or sex ratio among offspring. It is known that in acute anemic conditions, the chain synthesis is switched on to combat anoxic conditions due to a lowered hemoglobin level. We have estimated HbF levels in different genotypes, i. e. AA, AS & SS. The mean HhF levels were significantly elevated in SS genotype. This indicates that the γ chain synthesis is an alternative in acute hemolytic episodes due to the sickling.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 46, 号 3, p. 109-111, 発行日 1998-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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