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Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats
http://hdl.handle.net/10191/1953
http://hdl.handle.net/10191/19535b1e8f8f-193d-4357-9d19-47f6e626328d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00000007193.pdf (921.4 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-05-10 | |||||
| タイトル | ||||||
| タイトル | Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats | |||||
| タイトル | ||||||
| タイトル | Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vasopressin neuron | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | oxytocin neuron | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | osmosensitivity | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ovariectomy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | female rat | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Akaishi, Takao
× Akaishi, Takao |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study re-evaluated the osmosensitivity of the supraoptic (SON) vasopressin (AVP) and oxytocin (OXT) neurons in rats in vitro. Brain slice preparations made from ovariectomized (OVX) rats were incubated in 300 mOsm/kg H_2O artificial cerebrospinal fluid (ACSF) with low-Ca^<2+> (0.2 mM), and high-Mg^<2+> (5.0 mM), to block neuronal activation by way of synaptic inputs. Identified in this study by their discharge patterns according to Poulain and Wakerely were AVP neurons which had a phasic pattern, and OXT neurons, which showed a tonic pattern. In the phasic SON neurons (n=29,1.74±0.34 Hz, mean±SE), a significant (P<0.0005) increase in the mean discharge rate (5.59±0.77 Hz) was detected in the hyperosmolar condition (340mOsm/kg H_2O). In contrast to the phasic neurons, the SON neurons (n=14) with a continuous discharge pattern (7.25±1.11 Hz), did not show any significant change in the mean discharge rate in the same hyperosmolar condition (7.27±1.07 Hz). These results suggest that the OXT neuron but not the AVP neuron is much less sensitive to increased osmolality in OVX rats. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 47, 号 1, p. 1-7, 発行日 1999-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Akaishi, Takao, 1999, Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats: Niigata University School of Medicine, 1–7 p.
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