{"created":"2021-03-01T06:10:15.594390+00:00","id":6357,"links":{},"metadata":{"_buckets":{"deposit":"f9d835a8-3215-45b6-87a5-44bb62322bc8"},"_deposit":{"id":"6357","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6357"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006357","sets":["453:456","471:537:568:608"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"This study re-evaluated the osmosensitivity of the supraoptic (SON) vasopressin (AVP) and oxytocin (OXT) neurons in rats in vitro. Brain slice preparations made from ovariectomized (OVX) rats were incubated in 300 mOsm/kg H_2O artificial cerebrospinal fluid (ACSF) with low-Ca^<2+> (0.2 mM), and high-Mg^<2+> (5.0 mM), to block neuronal activation by way of synaptic inputs. Identified in this study by their discharge patterns according to Poulain and Wakerely were AVP neurons which had a phasic pattern, and OXT neurons, which showed a tonic pattern. In the phasic SON neurons (n=29,1.74±0.34 Hz, mean±SE), a significant (P<0.0005) increase in the mean discharge rate (5.59±0.77 Hz) was detected in the hyperosmolar condition (340mOsm/kg H_2O). In contrast to the phasic neurons, the SON neurons (n=14) with a continuous discharge pattern (7.25±1.11 Hz), did not show any significant change in the mean discharge rate in the same hyperosmolar condition (7.27±1.07 Hz). These results suggest that the OXT neuron but not the AVP neuron is much less sensitive to increased osmolality in OVX rats.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Akaishi, Takao"}],"nameIdentifiers":[{"nameIdentifier":"52534","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"KJ00000007193.pdf","filesize":[{"value":"921.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000007193.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6357/files/KJ00000007193.pdf"},"version_id":"9cc235af-6e85-4293-8d87-cff71944a3b3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"vasopressin neuron","subitem_subject_scheme":"Other"},{"subitem_subject":"oxytocin neuron","subitem_subject_scheme":"Other"},{"subitem_subject":"osmosensitivity","subitem_subject_scheme":"Other"},{"subitem_subject":"ovariectomy","subitem_subject_scheme":"Other"},{"subitem_subject":"female rat","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats"},{"subitem_title":"Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","608"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-05-10"},"publish_date":"2007-05-10","publish_status":"0","recid":"6357","relation_version_is_last":true,"title":["Responses to Osmotic Stimulation of Presumed Vasopressin and Oxytocin Neurons in the Supraoptic Nucleus of Ovariectomized Rats"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:38.793807+00:00"}