{"_buckets": {"deposit": "04a76329-fd4d-4c52-8648-2b3256a4ff19"}, "_deposit": {"id": "6317", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6317"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006317", "sets": ["456", "601"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2000-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "125", "bibliographicPageStart": "119", "bibliographicVolumeNumber": "48", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The intercellular adhesion molecule-1 (ICAM-1) is expressed on the surface of endothelial cells as well as neutrophils. Because neutrophils in the coronary circulation may play an important role in the progression of coronary artery disease, ICAM-1 and other adhesion molecules expressed on them were studied in the coronary circulation of patients with coronary artery disease. We used flow cytofluorometry to evaluate the amount of ICAM-1,CD18,and L-selectin expressed on neutrophils entering and leaving the coronary circulation in 18 patients who underwent coronary angiography. In addition, the serum level of the circulating form of ICAM-1 (cICAM-1) was measured in the same samples by using an enzyme-linked immunosorbent assay. Expression as the percentage of change between the left coronary artery and coronary sinus showed that neutrophil ICAM-1 (nICAM-1) decreased and serum cICAM-1 increased in patients with severe left coronary artery stenosis, compared with those with angiographically normal coronary arteries or only mild stenosis (nICAM-1,-9.7±2.9% vs 1.0±4.0%, p\u003c0.05; cICAM-1,6.3±1.9% vs 0.5±1.7%, p\u003c0.05,respectively). The changes in the expression of CD18 and L-selectin on neutrophils passing through the coronary circulation were not significant (CD18,-3.1±2.0% vs -3.8±4.3%; L-selectin, 6.0±3.6% vs -1.5±4.5%, respectively). ICAM-1 expressed on neutrophils appeared to be digested and relesed into plasma during passage through the coronary circulation in patients with severe stenotic coronary arteries. Thus, measurements of ICAM-1 may allow a prediction of the progression of coronary atherosclerosis.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "HIGUCHI, Kotaro"}], "nameIdentifiers": [{"nameIdentifier": "52315", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MATSUBARA, Taku"}], "nameIdentifiers": [{"nameIdentifier": "52316", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TOBA, Ken"}], "nameIdentifiers": [{"nameIdentifier": "52317", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HORI, Tomoyuki"}], "nameIdentifiers": [{"nameIdentifier": "52318", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "IDA, Toru"}], "nameIdentifiers": [{"nameIdentifier": "52319", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TAKEMOTO, Minoru"}], "nameIdentifiers": [{"nameIdentifier": "52320", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TAMURA, Yusuke"}], "nameIdentifiers": [{"nameIdentifier": "52321", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "YAMAZOE, Masaru"}], "nameIdentifiers": [{"nameIdentifier": "52322", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "OITE, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "52323", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "AIZAWA, Yoshifusa"}], "nameIdentifiers": [{"nameIdentifier": "52324", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000007272.pdf", "filesize": [{"value": "2.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2500000.0, "url": {"label": "KJ00000007272.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6317/files/KJ00000007272.pdf"}, "version_id": "501abc1d-745a-42ab-910c-24dea23eb162"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ICAM-1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "coronary artery disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "coronary circulation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Alterations in the Expression of Intercellular Adhesion Molecule-1(ICAM-1) on Neutrophils and in the Serum in the Coronary Circulationof Patients with Coronary Artery Disease", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Alterations in the Expression of Intercellular Adhesion Molecule-1(ICAM-1) on Neutrophils and in the Serum in the Coronary Circulationof Patients with Coronary Artery Disease"}, {"subitem_title": "Alterations in the Expression of Intercellular Adhesion Molecule-1(ICAM-1) on Neutrophils and in the Serum in the Coronary Circulationof Patients with Coronary Artery Disease", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "601"], "permalink_uri": "http://hdl.handle.net/10191/1912", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-05-10"}, "publish_date": "2007-05-10", "publish_status": "0", "recid": "6317", "relation": {}, "relation_version_is_last": true, "title": ["Alterations in the Expression of Intercellular Adhesion Molecule-1(ICAM-1) on Neutrophils and in the Serum in the Coronary Circulationof Patients with Coronary Artery Disease"], "weko_shared_id": null}