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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

Prognostic impact of indocyanine green plasma disappearance rate in hepatocellular carcinoma patients after radiofrequency ablation: A prognostic nomogram study.

http://hdl.handle.net/10191/47580
http://hdl.handle.net/10191/47580
f7a87227-78cf-43d3-9a2f-21fde74b4bb8
名前 / ファイル ライセンス アクション
h28nmk727.pdf 本文 (670.3 kB)
h28nmk727_a.pdf 要旨 (213.4 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2017-06-12
タイトル
タイトル Prognostic impact of indocyanine green plasma disappearance rate in hepatocellular carcinoma patients after radiofrequency ablation: A prognostic nomogram study.
タイトル
言語 en
タイトル Prognostic impact of indocyanine green plasma disappearance rate in hepatocellular carcinoma patients after radiofrequency ablation: A prognostic nomogram study.
言語
言語 eng
キーワード
主題Scheme Other
主題 Hepatocellular carcinoma
キーワード
主題Scheme Other
主題 indocyanine green plasma disappearance rate
キーワード
主題Scheme Other
主題 nomogram
キーワード
主題Scheme Other
主題 radiofrequency ablation
キーワード
主題Scheme Other
主題 des-gamma-carboxy prothrombin
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル ラジオ波焼灼術を施行した肝細胞癌患者に対するNomogramを用いた生命予後予測モデルの開発と血中ICG消失率測定の臨床的意義
著者 Azumi, Motoi

× Azumi, Motoi

WEKO 50957

Azumi, Motoi

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著者別名
識別子 50958
識別子Scheme WEKO
姓名 安住, 基
抄録
内容記述タイプ Abstract
内容記述 Objective: Radiofrequency ablation has been used widely for the local ablation of hepatocellular carcinoma, particularly in its early stages. The study aim was to identify significant prognostic factors and develop a predictive nomogram for patients with hepatocellular carcinoma who have undergone radiofrequency ablation. We also developed online software to predict the probability of 3- and 5-year overall survival based on clinical variables. Methods: We retrospectively studied 96 consecutive patients with hepatocellular carcinoma who had undergone radiofrequency ablation as a first-line treatment.Independent and significant factors affecting the overall survival were selected using a Cox proportional hazards model, and a prognostic nomogram was developed based on these factors. The predictive accuracy of the nomogram was determined by Harrell’s concordance index and compared with the Cancer of the Liver Italian Program score and Japan Integrated Staging score. Results: A multivariate analysis revealed that age, indocyanine green plasma disappearance rate, and log(des-gamma-carboxy prothrombin) level were independent and significant factors influencing the overall survival. The nomogram was based on these three factors. The mean concordance index of the nomogram was 0.74 ± 0.08, which was significantly better than that of conventional staging systems using the Cancer of the Liver Italian Program score (0.54 ± 0.03) and Japan Integrated Staging score (0.59 ± 0.07). Conclusions: This study suggested that the indocyanine green plasma disappearance rate and age at RFA and DCP are good predictors of the prognosis in hepatocellular carcinoma patients after radiofrequency ablation. We successfully developed a nomogram using obtainable variables before treatment.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(医学). 報告番号: 甲第4249号. 学位記番号: 新大院博(医)甲第727号. 学位授与年月日: 平成29年3月23日
書誌情報 発行日 2017-03-23
出版者
出版者 新潟大学
著者版フラグ
値 ETD
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2017-03-23
学位授与番号
学位授与番号 13101甲第4249号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)甲第727号
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