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Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences
http://hdl.handle.net/10191/27395
http://hdl.handle.net/10191/2739518d9a012-210e-414e-9cf1-df20eca7621c
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本文 (485.7 kB)
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要旨 (201.6 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2014-05-22 | |||||
| タイトル | ||||||
| タイトル | Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences | |||||
| タイトル | ||||||
| タイトル | Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | 口腔扁平上皮癌の切除断端における術中迅速病理診断の意義 : 局所再発に対する有効性の検討 | |||||
| 著者 |
Miyota, Shun
× Miyota, Shun |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 50343 | |||||
| 姓名 | 御代田, 駿 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background:Local recurrenceremains a challenging clinical issue for the treatment of oral squamous cell carcinoma (SCC).Weanalyzed retrospectively how effective the frozen section technique (FS)was against recurrences of oral SCC. Methods: We screened 343 surgical samples from 236 patients who hadoral SCC, carcinoma in-situ (CIS), or epithelial dysplasia, and we followed up their clinical outcomes for at least 5 years. The patients were classified into relapseand relapse-freegroupsaccording to the patients’ local recurrence histories, and theirhistopathological states of surgical margins were compared between primary and recurrent lesions. Result: Among the 236 patients,191 (80.9%, 191 samples; 115 males vs. 76 females) were classified into the relapse-free group, and 45 (19.1%, 152 samples, 27 females vs. 18 males)intothe relapse group.FS was more frequentlyperformedin the relapse-free group (128/191, 67.0%) than in the relapse group (83/152, 54.6%). Histopathologically,moderate dysplasia or CIS (borderline malignancies, BMs), and SCCwere recognized in 55 samples (43.0%) of the relapse-free group and in 57(68.7%) of the relapse group.For thosesurgicalmarginswith BMs, additional incisionswereperformed in 38 (69.1%) of the 55 relapse-free cases, which reduced to 20from the 38 BM margins (40% reduction), and in 39 (68.4%) of the 57 relapse cases (7.6% reduction). Conclusion:These results indicate thatthe intraoperative assessment of surgicalmarginsby FS is essential in preventing recurrencesof oral mucosal malignancies. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学位の種類: 博士（歯学）. 報告番号: 甲第3888号. 学位記番号: 新大院博（歯）甲第307号. 学位授与年月日: 平成26年3月24日 | |||||
| 書誌情報 | p. 1-23, 発行日 2014-03-24 | |||||
| 出版者 | ||||||
| 出版者 | 新潟大学 | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士（歯学） | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2014-03-24 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第3888号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博（歯）甲第307号 | |||||
