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  1. 260 大学院医歯学総合研究科(歯)
  2. 60 博士学位論文
  3. 10 博士学位論文
  1. 0 資料タイプ別
  2. 02 学位論文

Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences

http://hdl.handle.net/10191/27395
18d9a012-210e-414e-9cf1-df20eca7621c
名前 / ファイル ライセンス アクション
h25ndk307.pdf 本文 (485.7 kB)
h25ndk307_a.pdf 要旨 (201.6 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2014-05-22
タイトル
タイトル Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences
タイトル
言語 en
タイトル Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections : a practical clinicopathological management for recurrences
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル 口腔扁平上皮癌の切除断端における術中迅速病理診断の意義 : 局所再発に対する有効性の検討
著者 Miyota, Shun

× Miyota, Shun

WEKO 50342

Miyota, Shun

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著者別名
識別子
識別子 50343
識別子Scheme WEKO
姓名
姓名 御代田, 駿
抄録
内容記述タイプ Abstract
内容記述 Background:Local recurrenceremains a challenging clinical issue for the treatment of oral squamous cell carcinoma (SCC).Weanalyzed retrospectively how effective the frozen section technique (FS)was against recurrences of oral SCC. Methods: We screened 343 surgical samples from 236 patients who hadoral SCC, carcinoma in-situ (CIS), or epithelial dysplasia, and we followed up their clinical outcomes for at least 5 years. The patients were classified into relapseand relapse-freegroupsaccording to the patients’ local recurrence histories, and theirhistopathological states of surgical margins were compared between primary and recurrent lesions. Result: Among the 236 patients,191 (80.9%, 191 samples; 115 males vs. 76 females) were classified into the relapse-free group, and 45 (19.1%, 152 samples, 27 females vs. 18 males)intothe relapse group.FS was more frequentlyperformedin the relapse-free group (128/191, 67.0%) than in the relapse group (83/152, 54.6%). Histopathologically,moderate dysplasia or CIS (borderline malignancies, BMs), and SCCwere recognized in 55 samples (43.0%) of the relapse-free group and in 57(68.7%) of the relapse group.For thosesurgicalmarginswith BMs, additional incisionswereperformed in 38 (69.1%) of the 55 relapse-free cases, which reduced to 20from the 38 BM margins (40% reduction), and in 39 (68.4%) of the 57 relapse cases (7.6% reduction). Conclusion:These results indicate thatthe intraoperative assessment of surgicalmarginsby FS is essential in preventing recurrencesof oral mucosal malignancies.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(歯学). 報告番号: 甲第3888号. 学位記番号: 新大院博(歯)甲第307号. 学位授与年月日: 平成26年3月24日
書誌情報 p. 1-23, 発行日 2014-03-24
出版者
出版者 新潟大学
著者版フラグ
値 ETD
学位名
学位名 博士(歯学)
学位授与機関
学位授与機関名
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2014-03-24
学位授与番号
学位授与番号 13101甲第3888号
学位記番号
内容記述タイプ Other
内容記述 新大院博(歯)甲第307号
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