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透析期腎不全 4.透析患者の合併症 5)透析アミロイドーシス
http://hdl.handle.net/10191/9712
2d6b80b6-d0be-46e1-9245-99c6111fe597
名前 / ファイル | ライセンス | アクション | |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-16 | |||||
タイトル | ||||||
タイトル | 透析期腎不全 4.透析患者の合併症 5)透析アミロイドーシス | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 透析期腎不全 4.透析患者の合併症 5)透析アミロイドーシス | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dialysis-related amyloidosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β_2-microglobulin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β_2-m adsorption column | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | kidney transplantation | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
下条, 文武
× 下条, 文武× 高橋, 直生 |
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著者別名 | ||||||
識別子 | ||||||
識別子 | 47501 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | Gejyo, Fumitake | |||||
著者別名 | ||||||
識別子 | ||||||
識別子 | 47502 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | Takahashi, Naoki | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 長期透析治療をうけている患者に発症するアミロイドーシスは,透析アミロイドーシスと呼ばれ,その前駆蛋白は従来の透析膜では除去され難いβ_2-ミクログロブリン(β_2-m)である.本症の発症要因として,透析導入年齢が高いこと,透析期間が長いこと,生体適合性の低い透析膜あるいは純度の低い透析液を使用した場合,患者がアポリポ蛋白遺伝子E4を有する,などが明らかにされてきた.本症は,骨・関節障害を主病変とするため,QOLの低下をまねく深刻な透析合併症である.本症の予防・発症遅延対策として高性能膜透析器やβ_2-m吸着カラムが臨床に導入され,ある程度の効果をみている.しかし発症後の治療では限界があり,根本的な治療と考えられる腎移植を推進する必要がある. | |||||
書誌情報 |
日本内科学会雑誌 en : 日本内科学会雑誌 巻 89, 号 7, p. 1372-1378, 発行日 2000-07 |
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出版者 | ||||||
出版者 | 日本内科学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00215384 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00195836 | |||||
著者版フラグ | ||||||
値 | publisher |